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    Lrriq4 leucine-rich repeats and IQ motif containing 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100363341, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Lrriq4provided by RGD
    Official Full Name
    leucine-rich repeats and IQ motif containing 4provided by RGD
    Primary source
    RGD:2323202
    See related
    EnsemblRapid:ENSRNOG00000009004 AllianceGenome:RGD:2323202
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable protein serine/threonine phosphatase activity. Predicted to be involved in intracellular signal transduction. Predicted to be active in cytoplasm. Orthologous to human LRRIQ4 (leucine rich repeats and IQ motif containing 4). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 44.4), Lung (RPKM 21.6) and 5 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Lrriq4 in Genome Data Viewer
    Location:
    2q24
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (114657816..114685245, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (112729298..112756338, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (116347125..116372930, complement)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 4E, pseudogene 6 Neighboring gene heat shock protein family A (Hsp70) member 8, pseudogene 28 Neighboring gene leucine rich repeat containing 31 Neighboring gene leucine rich repeat containing 34 Neighboring gene myoneurin Neighboring gene transfer RNA valine (anticodon AAC) 1 Neighboring gene actin-related protein T3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    leucine-rich repeat and IQ domain-containing protein 4
    Names
    Lap1-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      114657816..114685245 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039103607.2 → XP_038959535.1  leucine-rich repeat and IQ domain-containing protein 4

      UniProtKB/TrEMBL
      F1M0Y2
      Related
      ENSRNOP00000011932.8, ENSRNOT00000011932.9
      Conserved Domains (3) summary
      PLN00113
      Location:90 → 494
      PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
      sd00033
      Location:297 → 319
      LRR_RI; leucine-rich repeat [structural motif]
      cd22307
      Location:530 → 598
      Adgb_C_mid-like; C-terminal middle region of Androglobins (Adgbs) and related proteins; including permuted globin domain and IQ motif
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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