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    Obp2a odorant binding protein 2A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 680754, updated on 9-Dec-2024

    Summary

    Official Symbol
    Obp2aprovided by RGD
    Official Full Name
    odorant binding protein 2Aprovided by RGD
    Primary source
    RGD:1588212
    See related
    AllianceGenome:RGD:1588212
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Lcn13; Obp2b
    Summary
    Predicted to enable odorant binding activity. Predicted to act upstream of or within several processes, including insulin receptor signaling pathway; negative regulation of gluconeogenesis; and regulation of lipid metabolic process. Predicted to be active in extracellular space. Orthologous to human OBP2A (odorant binding protein 2A) and OBP2B (odorant binding protein 2B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Uterus (RPKM 2.7), Testes (RPKM 2.4) and 5 other tissues See more
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    Genomic context

    See Obp2a in Genome Data Viewer
    Location:
    3p13
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (28904024..28907391)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (8505963..8509269)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (2908684..2913362)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene lipocalin 6 Neighboring gene lipocalin 10 Neighboring gene brain expressed myelocytomatosis oncogene Neighboring gene eukaryotic translation initiation factor 4E, pseudogene 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    odorant binding protein 2A
    Names
    lipocalin 13
    odorant binding protein 2B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001128139.3NP_001121611.1  odorant binding protein 2A precursor

      See identical proteins and their annotated locations for NP_001121611.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      A6JTA2, B3EY84, F7EU54
      Conserved Domains (1) summary
      pfam00061
      Location:31169
      Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      28904024..28907391
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063284542.1XP_063140612.1  odorant binding protein 2A isoform X1

    2. XM_063284544.1XP_063140614.1  odorant binding protein 2A isoform X2

      UniProtKB/TrEMBL
      A6JTA2, B3EY84, F7EU54
    3. XM_063284543.1XP_063140613.1  odorant binding protein 2A isoform X2

      UniProtKB/TrEMBL
      A6JTA2, B3EY84, F7EU54