Tti1 TELO2 interacting protein 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Tti1provided by RGD
Official Full Name: TELO2 interacting protein 1provided by RGD
Primary source: RGD:1562582
See related: EnsemblRapid:ENSRNOG00000012880 AllianceGenome:RGD:1562582
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1562582
Summary: Predicted to be involved in positive regulation of DNA damage checkpoint and regulation of TOR signaling. Predicted to be part of TORC1 complex; TORC2 complex; and TTT Hsp90 cochaperone complex. Predicted to be active in cytoplasm. Orthologous to human TTI1 (TELO2 interacting protein 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Adrenal (RPKM 112.4), Kidney (RPKM 95.2) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 3q42

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	3	NC_086021.1 (167058985..167102858, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	3	NC_051338.1 (146639048..146682945, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	3	NC_005102.4 (154463108..154506955, complement)

Chromosome 3 - NC_086021.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in positive regulation of DNA damage checkpoint	ISO Inferred from Sequence Orthology more info
involved_in regulation of TOR signaling	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
part_of TORC1 complex	ISO Inferred from Sequence Orthology more info
part_of TORC2 complex	ISO Inferred from Sequence Orthology more info
part_of TTT Hsp90 cochaperone complex	ISO Inferred from Sequence Orthology more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: TELO2-interacting protein 1 homolog

Names: TEL2-interacting protein 1 homolog; Tel2 interacting protein 1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.