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    Ndufb4 NADH:ubiquinone oxidoreductase subunit B4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 288088, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ndufb4provided by RGD
    Official Full Name
    NADH:ubiquinone oxidoreductase subunit B4provided by RGD
    Primary source
    RGD:1307072
    See related
    EnsemblRapid:ENSRNOG00000002721 AllianceGenome:RGD:1307072
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrial inner membrane and nucleoplasm. Predicted to be part of respiratory chain complex I. Orthologous to human NDUFB4 (NADH:ubiquinone oxidoreductase subunit B4). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 3032.6), Muscle (RPKM 1787.1) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Ndufb4 in Genome Data Viewer
    Location:
    11q21
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (76569178..76575879)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (63063723..63070426)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (65960277..65966899)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene follistatin-like 1 Neighboring gene uncharacterized LOC134481075 Neighboring gene ribosomal protein S11, pseudogene 13 Neighboring gene keratin, type II cytoskeletal 8-like Neighboring gene homogentisate 1, 2-dioxygenase

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in mitochondrial inner membrane  
    located_in mitochondrion  
    located_in nucleoplasm  
    part_of respiratory chain complex I  
    part_of respiratory chain complex I  

    General protein information

    Preferred Names
    NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4
    Names
    NADH dehydrogenase (ubiquinone) 1 beta subcomplex 4
    NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
    NP_001032415.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037338.2NP_001032415.1  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000011
      UniProtKB/TrEMBL
      D3ZV29, F1LPG5
      Related
      ENSRNOP00000003674.4, ENSRNOT00000003674.9
      Conserved Domains (1) summary
      pfam07225
      Location:5128
      NDUF_B4; NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      76569178..76575879
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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