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    Surf4 surfeit 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 619346, updated on 9-Dec-2024

    Summary

    Symbol
    Surf4provided by RGD
    Full Name
    surfeit 4provided by RGD
    Primary source
    RGD:1561980
    See related
    EnsemblRapid:ENSRNOG00000005247 AllianceGenome:RGD:1561980
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable COPII receptor activity. Predicted to be involved in several processes, including COPII-coated vesicle cargo loading; Golgi organization; and lipoprotein transport. Predicted to be located in Golgi apparatus; cytosol; and nuclear membrane. Predicted to be active in COPII-coated ER to Golgi transport vesicle; endoplasmic reticulum exit site; and endoplasmic reticulum-Golgi intermediate compartment. Orthologous to human SURF4 (surfeit 4). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 927.2), Adrenal (RPKM 775.5) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Surf4 in Genome Data Viewer
    Location:
    3p13
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (30646435..30659641, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (10248360..10261537, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (5468284..5481447, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORD36 Neighboring gene ribosomal protein L7A Neighboring gene SURF1, cytochrome c oxidase assembly factor Neighboring gene surfeit 2 Neighboring gene serine/threonine kinase-like domain containing 1 Neighboring gene REX4 homolog, 3'-5' exonuclease

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    Interactions

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables COPII receptor activity  
    enables cargo receptor activity  
    Component Evidence Code Pubs
    is_active_in COPII-coated ER to Golgi transport vesicle  
    located_in Golgi apparatus  
    located_in Golgi membrane  
    located_in cytosol  
    located_in endoplasmic reticulum  
    is_active_in endoplasmic reticulum exit site  
    located_in endoplasmic reticulum membrane  
    located_in endoplasmic reticulum-Golgi intermediate compartment  
    located_in endoplasmic reticulum-Golgi intermediate compartment membrane  
    located_in nuclear membrane  

    General protein information

    Preferred Names
    surfeit locus protein 4
    Names
    surfeit locus protein 4-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033868.1NP_001029040.1  surfeit locus protein 4

      See identical proteins and their annotated locations for NP_001029040.1

      Status: VALIDATED

      Source sequence(s)
      BQ192594, CA339301, CB703892, CB812667, CK358924, CO558944
      UniProtKB/TrEMBL
      A6JTJ4, D4A1D8
      Related
      ENSRNOP00000065447.4, ENSRNOT00000071754.4
      Conserved Domains (1) summary
      pfam02077
      Location:4269
      SURF4; SURF4 family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      30646435..30659641 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017592017.3XP_017447506.1  surfeit locus protein 4 isoform X1

      UniProtKB/TrEMBL
      D4A1D8
      Conserved Domains (1) summary
      cl21527
      Location:1226
      DoxX
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