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    Rsf1 remodeling and spacing factor 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 308839, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rsf1provided by RGD
    Official Full Name
    remodeling and spacing factor 1provided by RGD
    Primary source
    RGD:1311245
    See related
    EnsemblRapid:ENSRNOG00000024194 AllianceGenome:RGD:1311245
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Hbxap
    Summary
    Predicted to enable histone binding activity and histone octamer slider activity. Predicted to be involved in several processes, including nucleosome assembly; positive regulation of viral transcription; and regulation of DNA-templated transcription. Predicted to be located in nucleoplasm. Predicted to be part of RSF complex. Orthologous to human RSF1 (remodeling and spacing factor 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 93.3), Brain (RPKM 91.7) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Rsf1 in Genome Data Viewer
    Location:
    1q32
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (161303596..161426326)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (151892055..152015089)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (162549222..162671962)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene integrator complex subunit 4 Neighboring gene adipogenesis associated, Mth938 domain containing Neighboring gene ribosomal protein L35, pseudogene 4 Neighboring gene chloride nucleotide-sensitive channel 1A Neighboring gene aquaporin 11

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    NOT enables ATP hydrolysis activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables histone binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables histone octamer slider activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in DNA-templated transcription initiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in chromatin organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in chromatin remodeling ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in negative regulation of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in nucleosome assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of viral transcription ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of RSF complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of RSF complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    remodeling and spacing factor 1
    Names
    hepatitis B virus x associated protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427468.1NP_001414397.1  remodeling and spacing factor 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A6I6A8, D3ZGQ8
      Related
      ENSRNOP00000031549.6, ENSRNOT00000037050.7

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      161303596..161426326
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063262798.1XP_063118868.1  remodeling and spacing factor 1 isoform X1

      UniProtKB/TrEMBL
      A0A8I6GKD6, A6I6A8
      Related
      ENSRNOP00000092847.1, ENSRNOT00000098705.2
    2. XM_063262799.1XP_063118869.1  remodeling and spacing factor 1 isoform X2

      UniProtKB/TrEMBL
      A6I6B0