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    Prm1 protamine 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 24685, updated on 9-Dec-2024

    Summary

    Official Symbol
    Prm1provided by RGD
    Official Full Name
    protamine 1provided by RGD
    Primary source
    RGD:1583873
    See related
    AllianceGenome:RGD:1583873
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable DNA binding activity. Predicted to be involved in chromosome condensation and sperm DNA condensation. Predicted to act upstream of or within nucleus organization and spermatid development. Predicted to be located in cytosol; male germ cell nucleus; and nucleoplasm. Predicted to be part of nucleosome. Orthologous to human PRM1 (protamine 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 8501.2) See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Prm1 in Genome Data Viewer
    Location:
    10q11
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (5378740..5379235)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (4871817..4872312)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (4945995..4946241)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102552269 Neighboring gene RecQ mediated genome instability 2 Neighboring gene protamine 2 Neighboring gene protamine 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in chromosome condensation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within nucleus organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in sperm DNA condensation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within spermatid development ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    NOT located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in male germ cell nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    part_of nucleosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    sperm protamine P1
    Names
    cysteine-rich protamine
    protamine P1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002850.2NP_001002850.1  sperm protamine P1

      See identical proteins and their annotated locations for NP_001002850.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/Swiss-Prot
      A0JN03, P10118
      UniProtKB/TrEMBL
      A6K4I5

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      5378740..5379235
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)