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    Cbln3 cerebellin 3 precursor [ Rattus norvegicus (Norway rat) ]

    Gene ID: 501998, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cbln3provided by RGD
    Official Full Name
    cerebellin 3 precursorprovided by RGD
    Primary source
    RGD:1563731
    See related
    EnsemblRapid:ENSRNOG00000020503 AllianceGenome:RGD:1563731
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1563731
    Summary
    Predicted to be involved in maintenance of synapse structure. Predicted to be located in extracellular space. Predicted to be active in parallel fiber to Purkinje cell synapse and synaptic cleft. Orthologous to human CBLN3 (cerebellin 3 precursor). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 201.6), Liver (RPKM 106.5) and 1 other tissue See more
    Orthologs
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    Genomic context

    See Cbln3 in Genome Data Viewer
    Location:
    15p13
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (33331919..33334428, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (29362014..29364523, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (34548102..34550938, complement)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene receptor-interacting serine-threonine kinase 3 Neighboring gene nuclear factor of activated T-cells 4 Neighboring gene NYN domain and retroviral integrase containing Neighboring gene KH and NYN domain containing Neighboring gene short chain dehydrogenase/reductase family 39U, member 1 Neighboring gene transfer RNA alanine (anticodon AGC) 50

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in maintenance of synapse structure IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in extracellular space ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in parallel fiber to Purkinje cell synapse ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in synapse IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in synapse ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in synaptic cleft ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    cerebellin-3
    Names
    cerebellin 3 precursor protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109330.2NP_001102800.1  cerebellin-3 precursor

      See identical proteins and their annotated locations for NP_001102800.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000015
      UniProtKB/TrEMBL
      A6KH60, D3Z9H1
      Related
      ENSRNOP00000027794.2, ENSRNOT00000027794.5
      Conserved Domains (1) summary
      cl23878
      Location:63197
      C1q; C1q domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      33331919..33334428 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)