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    Mon1b MON1 homolog B, secretory trafficking associated [ Rattus norvegicus (Norway rat) ]

    Gene ID: 307868, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Mon1bprovided by RGD
    Official Full Name
    MON1 homolog B, secretory trafficking associatedprovided by RGD
    Primary source
    RGD:1309977
    See related
    EnsemblRapid:ENSRNOG00000084202 AllianceGenome:RGD:1309977
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1309977
    Summary
    Predicted to be involved in early viral transcription and late viral transcription. Predicted to be located in cytoplasm. Predicted to be part of Mon1-Ccz1 complex. Orthologous to human MON1B (MON1 homolog B, secretory trafficking associated). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 181.0), Thymus (RPKM 103.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Mon1b in Genome Data Viewer
    Location:
    19q12
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (58526503..58534478)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (41617372..41625347)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (45938433..45946647)

    Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134483647 Neighboring gene cell division cycle 34, ubiqiutin conjugating enzyme, pseudogene 1 Neighboring gene synaptonemal complex central element protein 1-like Neighboring gene small nucleolar RNA SNORA40 Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif, 18 Neighboring gene S-phase kinase-associated protein 1, pseudogene 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. HSV-1 stimulation-related protein HSRG1 inhibits viral gene transcriptional elongation by interacting with Cyclin T2. Wu W, et al. Sci China Life Sci, 2011 Apr. PMID 21509660
    2. Systematic Analysis of Human Cells Lacking ATG8 Proteins Uncovers Roles for GABARAPs and the CCZ1/MON1 Regulator C18orf8/RMC1 in Macroautophagic and Selective Autophagic Flux. Vaites LP, et al. Mol Cell Biol, 2018 Jan 1. PMID 29038162, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in early viral transcription ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in late viral transcription ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein targeting to vacuole IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of Mon1-Ccz1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Mon1-Ccz1 complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    vacuolar fusion protein MON1 homolog B
    Names
    MON1 secretory trafficking family member B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001399113.1 → NP_001386042.1  vacuolar fusion protein MON1 homolog B

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000019
      UniProtKB/TrEMBL
      A0A8I6G3S1, A6IZD1
      Conserved Domains (2) summary
      PHA03169
      Location:26 → 140
      PHA03169; hypothetical protein; Provisional
      pfam03164
      Location:144 → 561
      Mon1; Trafficking protein Mon1

    2. NM_001399114.1 → NP_001386043.1  vacuolar fusion protein MON1 homolog B

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000019
      UniProtKB/TrEMBL
      A0A8I6G3S1, A6IZD1
      Related
      ENSRNOP00000079817.1, ENSRNOT00000098873.2
      Conserved Domains (2) summary
      PHA03169
      Location:26 → 140
      PHA03169; hypothetical protein; Provisional
      pfam03164
      Location:144 → 561
      Mon1; Trafficking protein Mon1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086037.1 Reference GRCr8

      Range
      58526503..58534478
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001107433.1: Suppressed sequence

      Description
      NM_001107433.1: This RefSeq was removed because currently there is insufficient support for the transcript.
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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