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    Cimip2a ciliary microtubule inner protein 2A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 311797, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cimip2aprovided by RGD
    Official Full Name
    ciliary microtubule inner protein 2Aprovided by RGD
    Primary source
    RGD:1562762
    See related
    EnsemblRapid:ENSRNOG00000010019 AllianceGenome:RGD:1562762
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Fam166a
    Summary
    Predicted to be involved in flagellated sperm motility. Predicted to be located in ciliary basal body. Predicted to be active in axonemal A tubule inner sheath and sperm flagellum. Orthologous to human CIMIP2A (ciliary microtubule inner protein 2A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 269.5), Brain (RPKM 57.7) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Cimip2a in Genome Data Viewer
    Location:
    3p13
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (28429413..28437210)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (8030548..8038370)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (2434348..2441706)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L23-like Neighboring gene torsin family 4, member A Neighboring gene negative elongation factor complex member B Neighboring gene RNA, U6 small nuclear 136 Neighboring gene sperm-tail PG-rich repeat containing 3 Neighboring gene uncharacterized LOC120101506 Neighboring gene tubulin, beta 4B class IVb Neighboring gene solute carrier family 34 member 3 Neighboring gene ring finger protein 224

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Proteomic characterization of the human sperm nucleus. de Mateo S, et al. Proteomics, 2011 Jul. PMID 21630459
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC114439

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in flagellated sperm motility ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in flagellated sperm motility ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in axonemal A tubule inner sheath ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in axonemal A tubule inner sheath ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in ciliary basal body ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in sperm flagellum ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in sperm flagellum ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    ciliary microtubule inner protein 2A
    Names
    family with sequence similarity 166, member A
    protein FAM166A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025694.2 → NP_001020865.1  ciliary microtubule inner protein 2A

      See identical proteins and their annotated locations for NP_001020865.1

      Status: PROVISIONAL

      Source sequence(s)
      BC097396
      UniProtKB/Swiss-Prot
      Q4QR77
      UniProtKB/TrEMBL
      A6JT16
      Related
      ENSRNOP00000013335.2, ENSRNOT00000013335.6
      Conserved Domains (1) summary
      pfam10629
      Location:13 → 45
      DUF2475; Protein of unknown function (DUF2475)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      28429413..28437210
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039105194.2 → XP_038961122.1  ciliary microtubule inner protein 2A isoform X2

      Conserved Domains (1) summary
      pfam10629
      Location:13 → 45
      DUF2475; Protein of unknown function (DUF2475)

    2. XM_039105192.2 → XP_038961120.1  ciliary microtubule inner protein 2A isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4QR77.1 GenPept UniProtKB/Swiss-Prot:Q4QR77

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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