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    Stkld1 serine/threonine kinase-like domain containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 311825, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Stkld1provided by RGD
    Official Full Name
    serine/threonine kinase-like domain containing 1provided by RGD
    Primary source
    RGD:1307355
    See related
    EnsemblRapid:ENSRNOG00000027911 AllianceGenome:RGD:1307355
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1307355
    Summary
    Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in protein phosphorylation. Orthologous to human STKLD1 (serine/threonine kinase like domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 67.5), Thymus (RPKM 4.3) and 1 other tissue See more
    Orthologs
    human mouse all
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    Genomic context

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    See Stkld1 in Genome Data Viewer
    Location:
    3p13
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (30659659..30678650)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (10261583..10280850)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (5481524..5500568)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene SURF1, cytochrome c oxidase assembly factor Neighboring gene surfeit 2 Neighboring gene surfeit 4 Neighboring gene REX4 homolog, 3'-5' exonuclease Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif, 13 Neighboring gene uncharacterized LOC102548484 Neighboring gene calcium channel flower domain containing 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    serine/threonine kinase-like domain-containing protein STKLD1
    Names
    probable inactive protein kinase-like protein SgK071

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001395744.1 → NP_001382673.1  serine/threonine kinase-like domain-containing protein STKLD1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      A0A8J8XPK3, B1WBT9, F6R0A3
      Related
      ENSRNOP00000029627.8, ENSRNOT00000031316.7
      Conserved Domains (1) summary
      cl21453
      Location:4 → 268
      PKc_like; Protein Kinases, catalytic domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      30659659..30678650
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039105208.2 → XP_038961136.1  serine/threonine kinase-like domain-containing protein STKLD1 isoform X1

      UniProtKB/TrEMBL
      B1WBT9, F6R0A3
      Conserved Domains (1) summary
      cl21453
      Location:4 → 268
      PKc_like; Protein Kinases, catalytic domain

    2. XM_039105210.2 → XP_038961138.1  serine/threonine kinase-like domain-containing protein STKLD1 isoform X3

      UniProtKB/TrEMBL
      B1WBT9, F6R0A3
      Conserved Domains (1) summary
      cl21453
      Location:4 → 268
      PKc_like; Protein Kinases, catalytic domain

    3. XM_039105209.2 → XP_038961137.1  serine/threonine kinase-like domain-containing protein STKLD1 isoform X2

      UniProtKB/TrEMBL
      B1WBT9, F6R0A3
      Related
      ENSRNOP00000091000.2, ENSRNOT00000099497.2
      Conserved Domains (1) summary
      cl21453
      Location:4 → 268
      PKc_like; Protein Kinases, catalytic domain

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001107822.1: Suppressed sequence

      Description
      NM_001107822.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

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