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    Carhsp1 calcium regulated heat stable protein 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 260416, updated on 4-Jan-2025

    Summary

    Official Symbol
    Carhsp1provided by RGD
    Official Full Name
    calcium regulated heat stable protein 1provided by RGD
    Primary source
    RGD:708415
    See related
    EnsemblRapid:ENSRNOG00000002610 AllianceGenome:RGD:708415
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Crhsp24; Crhsp-24
    Summary
    Predicted to enable mRNA 3'-UTR binding activity. Predicted to be involved in regulation of mRNA stability. Predicted to be located in P granule and cytosol. Predicted to be part of cytoplasmic exosome (RNase complex). Predicted to be active in cytoplasm. Orthologous to human CARHSP1 (calcium regulated heat stable protein 1). [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Biased expression in Liver (RPKM 134.0), Lung (RPKM 105.1) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Carhsp1 in Genome Data Viewer
    Location:
    10q12
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (7453602..7467218)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (6946036..6960556)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (7041510..7055107)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 7 Neighboring gene cytochrome c oxidase subunit 6B1 pseudogene Neighboring gene LITAF domain containing Neighboring gene phosphomannomutase 2 Neighboring gene transmembrane protein 186

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables mRNA 3'-UTR binding  
    enables mRNA 3'-UTR binding  
    enables mRNA 3'-UTR binding  
    enables nucleic acid binding  
    Process Evidence Code Pubs
    involved_in regulation of mRNA stability  
    involved_in regulation of mRNA stability  
    involved_in regulation of mRNA stability  
    Component Evidence Code Pubs
    located_in P granule  
    located_in P granule  
    located_in P-body  
    is_active_in cytoplasm  
    part_of cytoplasmic exosome (RNase complex)  
    part_of cytoplasmic exosome (RNase complex)  
    located_in cytosol  
    located_in cytosol  

    General protein information

    Preferred Names
    calcium-regulated heat stable protein 1
    Names
    calcium-regulated heat-stable protein (24kD)
    calcium-regulated heat-stable protein of 24 kDa

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_152790.3NP_690003.1  calcium-regulated heat stable protein 1

      See identical proteins and their annotated locations for NP_690003.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/Swiss-Prot
      Q9WU49
      UniProtKB/TrEMBL
      A0A8I6AMM1, A6K4L7
      Related
      ENSRNOP00000102913.1, ENSRNOT00000158886.1
      Conserved Domains (1) summary
      cd04458
      Location:63128
      CSP_CDS; Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein. ...

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      7453602..7467218
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006245753.5XP_006245815.1  calcium-regulated heat stable protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZMT7, A0A8I6AMM1
      Related
      ENSRNOP00000003514.4, ENSRNOT00000003514.7
      Conserved Domains (1) summary
      cd04458
      Location:83148
      CSP_CDS; Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein. ...
    2. XM_039085307.2XP_038941235.2  calcium-regulated heat stable protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8I6AMM1
    3. XM_006245750.5XP_006245812.2  calcium-regulated heat stable protein 1 isoform X1

      UniProtKB/Swiss-Prot
      Q9WU49
      UniProtKB/TrEMBL
      A0A8I6AMM1, A6K4L7
      Conserved Domains (1) summary
      cd04458
      Location:63128
      CSP_CDS; Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein. ...
    4. XM_039085306.2XP_038941234.2  calcium-regulated heat stable protein 1 isoform X4

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