Slc6a20b solute carrier family 6 member 20b [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Slc6a20bprovided by RGD
Official Full Name: solute carrier family 6 member 20bprovided by RGD
Primary source: RGD:1566368
See related: EnsemblRapid:ENSRNOG00000006010 AllianceGenome:RGD:1566368
Gene type: protein coding
RefSeq status: MODEL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1566368
Summary: Enables L-proline transmembrane transporter activity; amino-acid betaine transmembrane transporter activity; and proline:sodium symporter activity. Involved in L-proline import across plasma membrane and amino-acid betaine transport. Predicted to be located in apical plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Kidney (RPKM 152.8), Brain (RPKM 19.6) and 1 other tissue See more
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Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	8	NC_086026.1 (132108481..132158422, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	8	NC_051343.1 (123234731..123278306, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	8	NC_005107.4 (132663281..132709485, complement)

Chromosome 8 - NC_086026.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables L-proline transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed
enables amino acid transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed
enables amino-acid betaine transmembrane transporter activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables proline:sodium symporter activity	IDA Inferred from Direct Assay more info	PubMed
enables proline:sodium symporter activity	ISS Inferred from Sequence or Structural Similarity more info
enables solute:sodium symporter activity	ISS Inferred from Sequence or Structural Similarity more info
enables symporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in L-proline import across plasma membrane	IDA Inferred from Direct Assay more info	PubMed
involved_in amino acid import across plasma membrane	IDA Inferred from Direct Assay more info	PubMed
involved_in amino acid transport	IDA Inferred from Direct Assay more info	PubMed
involved_in amino-acid betaine transport	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in glycine import across plasma membrane	ISS Inferred from Sequence or Structural Similarity more info
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in apical plasma membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

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The following sections contain reference sequences that belong to a specific genome build. Explain

XM_063266353.1 → XP_063122423.1 sodium- and chloride-dependent transporter XTRP3B isoform X2

UniProtKB/TrEMBL

F1LZT7
XM_002729986.7 → XP_002730032.2 sodium- and chloride-dependent transporter XTRP3B isoform X1

See identical proteins and their annotated locations for XP_002730032.2

UniProtKB/Swiss-Prot

Q64093

UniProtKB/TrEMBL

A0A8I6AX01

Related

ENSRNOP00000008172.8, ENSRNOT00000008172.9

Conserved Domains (1) summary

cl00456
Location:43 → 618

SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain