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    Aif1l allograft inflammatory factor 1-like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362107, updated on 9-Dec-2024

    Summary

    Official Symbol
    Aif1lprovided by RGD
    Official Full Name
    allograft inflammatory factor 1-likeprovided by RGD
    Primary source
    RGD:1305081
    See related
    EnsemblRapid:ENSRNOG00000009951 AllianceGenome:RGD:1305081
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1305081
    Summary
    Predicted to enable actin filament binding activity and calcium ion binding activity. Predicted to be involved in actin filament bundle assembly and ruffle assembly. Part of protein-containing complex. Orthologous to human AIF1L (allograft inflammatory factor 1 like). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 1550.1), Adrenal (RPKM 198.4) and 2 other tissues See more
    Orthologs
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    Genomic context

    See Aif1l in Genome Data Viewer
    Location:
    3p12
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (35627239..35651793)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (15229476..15254033)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (9237944..9262628, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134486281 Neighboring gene laminin subunit gamma 3 Neighboring gene nucleoporin 214 Neighboring gene family with sequence similarity 78, member A

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables actin filament binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in actin filament bundle assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ruffle assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in actin cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with actin filament IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in actin filament ISO
    Inferred from Sequence Orthology
    more info
     
    located_in focal adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    part_of protein-containing complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    colocalizes_with ruffle membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    allograft inflammatory factor 1-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108578.1NP_001102048.1  allograft inflammatory factor 1-like

      See identical proteins and their annotated locations for NP_001102048.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474001
      UniProtKB/TrEMBL
      A6JU37
      Related
      ENSRNOP00000013286.6, ENSRNOT00000013286.7
      Conserved Domains (1) summary
      PTZ00184
      Location:47115
      PTZ00184; calmodulin; Provisional

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      35627239..35651793
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)