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    Glb1l galactosidase, beta 1-like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 301525, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Glb1lprovided by RGD
    Official Full Name
    galactosidase, beta 1-likeprovided by RGD
    Primary source
    RGD:1309474
    See related
    EnsemblRapid:ENSRNOG00000019243 AllianceGenome:RGD:1309474
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable beta-galactosidase activity. Predicted to be involved in galactose catabolic process. Predicted to be active in vacuole. Orthologous to human GLB1L (galactosidase beta 1 like). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 145.2), Testes (RPKM 127.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Glb1l in Genome Data Viewer
    Location:
    9q33
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (84141993..84154176, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (76693325..76705548, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (82400457..82410970, complement)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene ATP binding cassette subfamily B member 6 Neighboring gene autophagy related 9A Neighboring gene ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1 Neighboring gene serine/threonine kinase 16 Neighboring gene uncharacterized LOC102554903 Neighboring gene tubulin, alpha 4A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c. Abonnenc M, et al. Circ Res, 2013 Oct 25. PMID 24006456
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables beta-galactosidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in galactose catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in vacuole IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    beta-galactosidase-1-like protein
    NP_001121001.1
    XP_008765447.1
    XP_038939293.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001127529.2 → NP_001121001.1  beta-galactosidase-1-like protein precursor

      See identical proteins and their annotated locations for NP_001121001.1

      Status: PROVISIONAL

      Source sequence(s)
      BC161869
      UniProtKB/TrEMBL
      B1WBS6, F7FBB9
      Related
      ENSRNOP00000026081.4, ENSRNOT00000026081.7
      Conserved Domains (1) summary
      pfam01301
      Location:34 → 349
      Glyco_hydro_35; Glycosyl hydrolases family 35

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      84141993..84154176 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008767225.4 → XP_008765447.1  beta-galactosidase-1-like protein isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZK37
      Conserved Domains (1) summary
      cl07893
      Location:34 → 259
      AmyAc_family; Alpha amylase catalytic domain family

    2. XM_039083365.2 → XP_038939293.1  beta-galactosidase-1-like protein isoform X1

      Conserved Domains (1) summary
      pfam01301
      Location:34 → 349
      Glyco_hydro_35; Glycosyl hydrolases family 35
    Nucleotide Protein Strain
    Heading Accession and Version

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