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    Fhad1 forkhead associated phosphopeptide binding domain 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500577, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Fhad1provided by RGD
    Official Full Name
    forkhead associated phosphopeptide binding domain 1provided by RGD
    Primary source
    RGD:1563444
    See related
    EnsemblRapid:ENSRNOG00000028064 AllianceGenome:RGD:1563444
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1563444
    Summary
    Orthologous to human FHAD1 (forkhead associated phosphopeptide binding domain 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 121.0) and Lung (RPKM 45.5) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Fhad1 in Genome Data Viewer
    Location:
    5q36
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (159474111..159593455, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (154191593..154310442, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (160438575..160555103, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120103027 Neighboring gene EF-hand domain family, member D2 Neighboring gene chymotrypsin C Neighboring gene transmembrane protein 51 Neighboring gene uncharacterized LOC134487032 Neighboring gene kazrin, periplakin interacting protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. FMRP recruitment of β-catenin to the translation pre-initiation complex represses translation. Ehyai S, et al. EMBO Rep, 2018 Dec. PMID 30361391, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC116177

    General protein information

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    Preferred Names
    forkhead-associated domain-containing protein 1
    Names
    forkhead-associated (FHA) phosphopeptide binding domain 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001044268.2 → NP_001037733.2  forkhead-associated domain-containing protein 1

      Status: VALIDATED

      Source sequence(s)
      BC098024, JAXUCZ010000005
      UniProtKB/TrEMBL
      A0A140UHW9
      Related
      ENSRNOP00000018953.7, ENSRNOT00000018953.9
      Conserved Domains (2) summary
      COG1196
      Location:230 → 926
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam00498
      Location:18 → 84
      FHA; FHA domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      159474111..159593455 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039110639.2 → XP_038966567.1  forkhead-associated domain-containing protein 1 isoform X6

      Conserved Domains (2) summary
      COG1196
      Location:230 → 846
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam00498
      Location:18 → 84
      FHA; FHA domain

    2. XM_063288294.1 → XP_063144364.1  forkhead-associated domain-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZQ37
      Related
      ENSRNOP00000080164.1, ENSRNOT00000095076.2

    3. XM_039110637.2 → XP_038966565.1  forkhead-associated domain-containing protein 1 isoform X3

      Conserved Domains (2) summary
      TIGR02168
      Location:229 → 1020
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam00498
      Location:18 → 84
      FHA; FHA domain

    4. XM_039110638.2 → XP_038966566.1  forkhead-associated domain-containing protein 1 isoform X5

      Conserved Domains (2) summary
      COG1196
      Location:243 → 882
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam00498
      Location:18 → 84
      FHA; FHA domain

    5. XM_039110641.2 → XP_038966569.1  forkhead-associated domain-containing protein 1 isoform X8

      Conserved Domains (3) summary
      TIGR00618
      Location:648 → 1206
      sbcc; exonuclease SbcC
      COG1196
      Location:230 → 926
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam00498
      Location:18 → 84
      FHA; FHA domain

    6. XM_039110640.2 → XP_038966568.1  forkhead-associated domain-containing protein 1 isoform X7

      Conserved Domains (3) summary
      PTZ00121
      Location:648 → 1248
      PTZ00121; MAEBL; Provisional
      COG1196
      Location:230 → 926
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam00498
      Location:18 → 84
      FHA; FHA domain

    7. XM_063288296.1 → XP_063144366.1  forkhead-associated domain-containing protein 1 isoform X4

    8. XM_039110636.2 → XP_038966564.1  forkhead-associated domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A140UHW9
      Conserved Domains (2) summary
      COG1196
      Location:230 → 926
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam00498
      Location:18 → 84
      FHA; FHA domain

    9. XM_039110642.2 → XP_038966570.1  forkhead-associated domain-containing protein 1 isoform X9

      Conserved Domains (3) summary
      PTZ00121
      Location:648 → 1207
      PTZ00121; MAEBL; Provisional
      COG1196
      Location:230 → 926
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam00498
      Location:18 → 84
      FHA; FHA domain

    10. XM_039110643.2 → XP_038966571.1  forkhead-associated domain-containing protein 1 isoform X10

      Conserved Domains (3) summary
      COG1196
      Location:230 → 926
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      COG5022
      Location:740 → 1136
      COG5022; Myosin heavy chain [General function prediction only]
      pfam00498
      Location:18 → 84
      FHA; FHA domain

    11. XM_063288297.1 → XP_063144367.1  forkhead-associated domain-containing protein 1 isoform X11

    Nucleotide Protein Strain
    Heading Accession and Version

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