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    Baz1a bromodomain adjacent to zinc finger domain, 1A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 314126, updated on 27-Dec-2024

    Summary

    Official Symbol
    Baz1aprovided by RGD
    Official Full Name
    bromodomain adjacent to zinc finger domain, 1Aprovided by RGD
    Primary source
    RGD:1306199
    See related
    EnsemblRapid:ENSRNOG00000006828 AllianceGenome:RGD:1306199
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable DNA binding activity. Predicted to be involved in DNA-templated DNA replication; nucleosome assembly; and regulation of macromolecule metabolic process. Predicted to be located in nucleus and pericentric heterochromatin. Predicted to be part of ACF complex and CHRAC. Predicted to be active in nuclear chromosome. Orthologous to human BAZ1A (bromodomain adjacent to zinc finger domain 1A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 234.1), Spleen (RPKM 151.2) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Baz1a in Genome Data Viewer
    Location:
    6q23
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (78124872..78247672, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (72389701..72512516, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (75793223..75873854, complement)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene cofilin 2 Neighboring gene uncharacterized LOC108351236 Neighboring gene U6 spliceosomal RNA Neighboring gene RIKEN cDNA 2700097009 gene like Neighboring gene signal recognition particle 54A Neighboring gene uncharacterized LOC134479210 Neighboring gene family with sequence similarity 177, member A1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding  
    enables metal ion binding  
    Process Evidence Code Pubs
    involved_in DNA-templated DNA replication  
    involved_in biological_process  
    involved_in chromatin remodeling  
    involved_in nucleosome assembly  
    involved_in positive regulation of DNA replication  
    involved_in positive regulation of DNA replication  
    involved_in regulation of DNA replication  
    involved_in regulation of DNA-templated transcription  
    involved_in regulation of heterochromatin formation  
    Component Evidence Code Pubs
    part_of ACF complex  
    part_of CHRAC  
    part_of CHRAC  
    is_active_in nuclear chromosome  
    located_in nuclear chromosome  
    located_in nucleus  
    located_in pericentric heterochromatin  

    General protein information

    Preferred Names
    bromodomain adjacent to zinc finger domain protein 1A

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001170568.2NP_001164039.2  bromodomain adjacent to zinc finger domain protein 1A

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006
      UniProtKB/TrEMBL
      F1M4U9
      Related
      ENSRNOP00000009080.7, ENSRNOT00000009080.9
      Conserved Domains (7) summary
      cd05504
      Location:14191532
      Bromo_Acf1_like; Bromodomain; Acf1_like or BAZ1A_like subfamily. Bromo adjacent to zinc finger 1A (BAZ1A) was identified as a novel human bromodomain gene by cDNA library screening. The Drosophila homologue, Acf1, is part of the CHRAC (chromatin accessibility complex) ...
      PTZ00121
      Location:646793
      PTZ00121; MAEBL; Provisional
      smart00571
      Location:422483
      DDT; domain in different transcription and chromosome remodeling factors
      cd15627
      Location:11471192
      PHD_BAZ1A; PHD finger found in bromodomain adjacent to zinc finger domain protein 1A (BAZ1A)
      pfam10537
      Location:23122
      WAC_Acf1_DNA_bd; ATP-utilising chromatin assembly and remodelling N-terminal
      pfam15612
      Location:590635
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:799925
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      78124872..78247672 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063261906.1XP_063117976.1  bromodomain adjacent to zinc finger domain protein 1A isoform X2

    2. XM_039112223.2XP_038968151.1  bromodomain adjacent to zinc finger domain protein 1A isoform X1

      Conserved Domains (7) summary
      cd05504
      Location:14491562
      Bromo_Acf1_like; Bromodomain; Acf1_like or BAZ1A_like subfamily. Bromo adjacent to zinc finger 1A (BAZ1A) was identified as a novel human bromodomain gene by cDNA library screening. The Drosophila homologue, Acf1, is part of the CHRAC (chromatin accessibility complex) ...
      PTZ00121
      Location:646793
      PTZ00121; MAEBL; Provisional
      smart00571
      Location:422483
      DDT; domain in different transcription and chromosome remodeling factors
      cd15627
      Location:11771222
      PHD_BAZ1A; PHD finger found in bromodomain adjacent to zinc finger domain protein 1A (BAZ1A)
      pfam10537
      Location:23122
      WAC_Acf1_DNA_bd; ATP-utilising chromatin assembly and remodelling N-terminal
      pfam15612
      Location:590635
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:799925
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
    3. XM_063261908.1XP_063117978.1  bromodomain adjacent to zinc finger domain protein 1A isoform X3

      UniProtKB/TrEMBL
      A0A8I6G4X5
    4. XM_063261907.1XP_063117977.1  bromodomain adjacent to zinc finger domain protein 1A isoform X3

      UniProtKB/TrEMBL
      A0A8I6G4X5
      Related
      ENSRNOP00000079177.1, ENSRNOT00000098593.2
    5. XM_063261905.1XP_063117975.1  bromodomain adjacent to zinc finger domain protein 1A isoform X2

    6. XM_039112222.2XP_038968150.1  bromodomain adjacent to zinc finger domain protein 1A isoform X1

      Conserved Domains (7) summary
      cd05504
      Location:14491562
      Bromo_Acf1_like; Bromodomain; Acf1_like or BAZ1A_like subfamily. Bromo adjacent to zinc finger 1A (BAZ1A) was identified as a novel human bromodomain gene by cDNA library screening. The Drosophila homologue, Acf1, is part of the CHRAC (chromatin accessibility complex) ...
      PTZ00121
      Location:646793
      PTZ00121; MAEBL; Provisional
      smart00571
      Location:422483
      DDT; domain in different transcription and chromosome remodeling factors
      cd15627
      Location:11771222
      PHD_BAZ1A; PHD finger found in bromodomain adjacent to zinc finger domain protein 1A (BAZ1A)
      pfam10537
      Location:23122
      WAC_Acf1_DNA_bd; ATP-utilising chromatin assembly and remodelling N-terminal
      pfam15612
      Location:590635
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:799925
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
    7. XM_039112224.2XP_038968152.1  bromodomain adjacent to zinc finger domain protein 1A isoform X2

      Conserved Domains (7) summary
      cd05504
      Location:14171530
      Bromo_Acf1_like; Bromodomain; Acf1_like or BAZ1A_like subfamily. Bromo adjacent to zinc finger 1A (BAZ1A) was identified as a novel human bromodomain gene by cDNA library screening. The Drosophila homologue, Acf1, is part of the CHRAC (chromatin accessibility complex) ...
      PTZ00121
      Location:614761
      PTZ00121; MAEBL; Provisional
      smart00571
      Location:422483
      DDT; domain in different transcription and chromosome remodeling factors
      cd15627
      Location:11451190
      PHD_BAZ1A; PHD finger found in bromodomain adjacent to zinc finger domain protein 1A (BAZ1A)
      pfam10537
      Location:23122
      WAC_Acf1_DNA_bd; ATP-utilising chromatin assembly and remodelling N-terminal
      pfam15612
      Location:558603
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:767893
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
    8. XM_039112225.2XP_038968153.1  bromodomain adjacent to zinc finger domain protein 1A isoform X3

      UniProtKB/TrEMBL
      A0A8I6G4X5
      Conserved Domains (7) summary
      cd05504
      Location:13871500
      Bromo_Acf1_like; Bromodomain; Acf1_like or BAZ1A_like subfamily. Bromo adjacent to zinc finger 1A (BAZ1A) was identified as a novel human bromodomain gene by cDNA library screening. The Drosophila homologue, Acf1, is part of the CHRAC (chromatin accessibility complex) ...
      PTZ00121
      Location:614761
      PTZ00121; MAEBL; Provisional
      smart00571
      Location:422483
      DDT; domain in different transcription and chromosome remodeling factors
      cd15627
      Location:11151160
      PHD_BAZ1A; PHD finger found in bromodomain adjacent to zinc finger domain protein 1A (BAZ1A)
      pfam10537
      Location:23122
      WAC_Acf1_DNA_bd; ATP-utilising chromatin assembly and remodelling N-terminal
      pfam15612
      Location:558603
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:767893
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
    9. XM_063261904.1XP_063117974.1  bromodomain adjacent to zinc finger domain protein 1A isoform X2

    10. XM_039112221.1XP_038968149.1  bromodomain adjacent to zinc finger domain protein 1A isoform X1

      Conserved Domains (7) summary
      cd05504
      Location:14491562
      Bromo_Acf1_like; Bromodomain; Acf1_like or BAZ1A_like subfamily. Bromo adjacent to zinc finger 1A (BAZ1A) was identified as a novel human bromodomain gene by cDNA library screening. The Drosophila homologue, Acf1, is part of the CHRAC (chromatin accessibility complex) ...
      PTZ00121
      Location:646793
      PTZ00121; MAEBL; Provisional
      smart00571
      Location:422483
      DDT; domain in different transcription and chromosome remodeling factors
      cd15627
      Location:11771222
      PHD_BAZ1A; PHD finger found in bromodomain adjacent to zinc finger domain protein 1A (BAZ1A)
      pfam10537
      Location:23122
      WAC_Acf1_DNA_bd; ATP-utilising chromatin assembly and remodelling N-terminal
      pfam15612
      Location:590635
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:799925
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
    11. XM_063261909.1XP_063117979.1  bromodomain adjacent to zinc finger domain protein 1A isoform X4

    12. XM_039112227.2XP_038968155.1  bromodomain adjacent to zinc finger domain protein 1A isoform X6

      UniProtKB/TrEMBL
      A6HBL3
      Conserved Domains (5) summary
      cd05504
      Location:9331046
      Bromo_Acf1_like; Bromodomain; Acf1_like or BAZ1A_like subfamily. Bromo adjacent to zinc finger 1A (BAZ1A) was identified as a novel human bromodomain gene by cDNA library screening. The Drosophila homologue, Acf1, is part of the CHRAC (chromatin accessibility complex) ...
      PTZ00121
      Location:130277
      PTZ00121; MAEBL; Provisional
      cd15627
      Location:661706
      PHD_BAZ1A; PHD finger found in bromodomain adjacent to zinc finger domain protein 1A (BAZ1A)
      pfam15612
      Location:74119
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:283409
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
    13. XM_039112226.2XP_038968154.1  bromodomain adjacent to zinc finger domain protein 1A isoform X5

      UniProtKB/TrEMBL
      A6HBL3
      Conserved Domains (5) summary
      cd05504
      Location:9651078
      Bromo_Acf1_like; Bromodomain; Acf1_like or BAZ1A_like subfamily. Bromo adjacent to zinc finger 1A (BAZ1A) was identified as a novel human bromodomain gene by cDNA library screening. The Drosophila homologue, Acf1, is part of the CHRAC (chromatin accessibility complex) ...
      PTZ00121
      Location:162309
      PTZ00121; MAEBL; Provisional
      cd15627
      Location:693738
      PHD_BAZ1A; PHD finger found in bromodomain adjacent to zinc finger domain protein 1A (BAZ1A)
      pfam15612
      Location:106151
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:315441
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
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