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    Rbm24 RNA binding motif protein 24 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 690139, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rbm24provided by RGD
    Official Full Name
    RNA binding motif protein 24provided by RGD
    Primary source
    RGD:1584029
    See related
    AllianceGenome:RGD:1584029
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable RNA binding activity. Involved in regulation of alternative mRNA splicing, via spliceosome. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be active in cytosol and nucleus. Orthologous to human RBM24 (RNA binding motif protein 24). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 411.6), Heart (RPKM 371.1) and 3 other tissues See more
    Orthologs
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    Genomic context

    See Rbm24 in Genome Data Viewer
    Location:
    17p14
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (18481893..18494440, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (18275681..18288231, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (18671037..18682876, complement)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene cyclase associated actin cytoskeleton regulatory protein 2 Neighboring gene uncharacterized LOC120097855 Neighboring gene zinc finger protein 120 like 3 Neighboring gene uncharacterized LOC134482795 Neighboring gene stathmin domain containing 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA binding  
    enables mRNA 3'-UTR AU-rich region binding  
    enables mRNA 3'-UTR binding  
    enables mRNA 3'-UTR binding  
    enables mRNA CDS binding  
    enables pre-mRNA intronic binding  
    enables sequence-specific mRNA binding  
    Process Evidence Code Pubs
    involved_in 3'-UTR-mediated mRNA destabilization  
    involved_in DNA damage response  
    involved_in RNA splicing  
    involved_in cell differentiation  
    involved_in endocardial cushion development  
    involved_in mRNA destabilization  
    involved_in mRNA processing  
    involved_in mRNA stabilization  
    involved_in mRNA stabilization  
    involved_in negative regulation of cytoplasmic translation  
    involved_in positive regulation of 3'-UTR-mediated mRNA stabilization  
    involved_in positive regulation of myotube differentiation  
    involved_in positive regulation of myotube differentiation  
    involved_in positive regulation of skeletal muscle fiber differentiation  
    involved_in positive regulation of stem cell differentiation  
    involved_in regulation of alternative mRNA splicing, via spliceosome  
    involved_in regulation of alternative mRNA splicing, via spliceosome PubMed 
    involved_in regulation of alternative mRNA splicing, via spliceosome  
    involved_in regulation of mRNA stability  
    involved_in regulation of myotube differentiation  
    involved_in regulation of translation  
    Component Evidence Code Pubs
    located_in cytoplasm  
    located_in cytoplasm  
    is_active_in cytosol  
    located_in cytosol  
    located_in nucleoplasm  
    is_active_in nucleus  
    located_in nucleus  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191100.1NP_001178029.1  RNA-binding protein 24

      Status: INFERRED

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/Swiss-Prot
      M0R7T6
      Conserved Domains (1) summary
      cd12384
      Location:1186
      RRM_RBM24_RBM38_like; RNA recognition motif (RRM) found in eukaryotic RNA-binding protein RBM24, RBM38 and similar proteins

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      18481893..18494440 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_005495334.2 RNA Sequence

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