Rpp38 ribonuclease P/MRP subunit p38 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Rpp38provided by RGD
Official Full Name: ribonuclease P/MRP subunit p38provided by RGD
Primary source: RGD:1307474
See related: EnsemblRapid:ENSRNOG00000063181 AllianceGenome:RGD:1307474
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable ribonuclease P RNA binding activity. Predicted to contribute to ribonuclease P activity. Predicted to be involved in tRNA 5'-leader removal. Predicted to be located in nucleolus. Predicted to be part of multimeric ribonuclease P complex. Predicted to be active in fibrillar center. Orthologous to human RPP38 (ribonuclease P/MRP subunit p38). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Adrenal (RPKM 40.4), Testes (RPKM 36.7) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 17q12.3

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	17	NC_086035.1 (79823237..79826908)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	17	NC_051352.1 (74914066..74917742)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	17	NC_005116.4 (78915450..78919144)

Chromosome 17 - NC_086035.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH137116 (e-PCR)
- UniSTS:219204

D17Got93 (e-PCR)
- UniSTS:112196

RH127990 (e-PCR)
- UniSTS:211300

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables ribonuclease P RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables ribonuclease P RNA binding	ISO Inferred from Sequence Orthology more info
contributes_to ribonuclease P activity	IBA Inferred from Biological aspect of Ancestor more info
contributes_to ribonuclease P activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in tRNA 5'-leader removal	IBA Inferred from Biological aspect of Ancestor more info
involved_in tRNA 5'-leader removal	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in fibrillar center	IBA Inferred from Biological aspect of Ancestor more info
located_in fibrillar center	ISO Inferred from Sequence Orthology more info
part_of multimeric ribonuclease P complex	IBA Inferred from Biological aspect of Ancestor more info
part_of multimeric ribonuclease P complex	ISO Inferred from Sequence Orthology more info
part_of nucleolar ribonuclease P complex	IEA Inferred from Electronic Annotation more info
located_in nucleolus	ISO Inferred from Sequence Orthology more info
part_of ribonuclease MRP complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ribonuclease P protein subunit p38

Names: ribonuclease P/MRP 38 subunit; ribonuclease P/MRP 38kDa subunit

NP_001028235.1

EC 3.1.26.5

XP_006254330.1

EC 3.1.26.5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.