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    Ccnyl1 cyclin Y-like 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 316452, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ccnyl1provided by RGD
    Official Full Name
    cyclin Y-like 1provided by RGD
    Primary source
    RGD:1310683
    See related
    EnsemblRapid:ENSRNOG00000023807 AllianceGenome:RGD:1310683
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1310683
    Summary
    Predicted to enable protein kinase binding activity. Predicted to be involved in neurogenesis and regulation of canonical Wnt signaling pathway. Predicted to act upstream of or within flagellated sperm motility; regulation of protein kinase activity; and spermatogenesis. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human CCNYL1 (cyclin Y like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 156.4), Muscle (RPKM 49.0) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ccnyl1 in Genome Data Viewer
    Location:
    9q32
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (73565484..73601926)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (66071721..66121742)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (71398186..71434581)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134480378 Neighboring gene uncharacterized LOC120094695 Neighboring gene uncharacterized LOC134480380 Neighboring gene basic proline-rich protein-like Neighboring gene frizzled class receptor 5 Neighboring gene pleckstrin homology domain containing M3 Neighboring gene uncharacterized LOC120094696

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Post-transcriptional Wnt Signaling Governs Epididymal Sperm Maturation. Koch S, et al. Cell, 2015 Nov 19. PMID 26590424
    2. CCNYL1, but Not CCNY, Cooperates with CDK16 to Regulate Spermatogenesis in Mouse. Zi Z, et al. PLoS Genet, 2015 Aug. PMID 26305884, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables protein kinase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within flagellated sperm motility ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of canonical Wnt signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within regulation of protein kinase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within regulation of protein phosphorylation ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within spermatogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    cyclin-Y-like protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      73565484..73601926
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008767164.4 → XP_008765386.1  cyclin-Y-like protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZUQ3
      Related
      ENSRNOP00000047323.5, ENSRNOT00000049411.7
      Conserved Domains (1) summary
      pfam00134
      Location:169 → 291
      Cyclin_N; Cyclin, N-terminal domain

    2. XM_063267898.1 → XP_063123968.1  cyclin-Y-like protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZUQ3
    Nucleotide Protein Strain
    Heading Accession and Version

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