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    Syce1 synaptonemal complex central element protein 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 502372, updated on 9-Dec-2024

    Summary

    Official Symbol
    Syce1provided by RGD
    Official Full Name
    synaptonemal complex central element protein 1provided by RGD
    Primary source
    RGD:1559853
    See related
    EnsemblRapid:ENSRNOG00000024073 AllianceGenome:RGD:1559853
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in cell division and synaptonemal complex assembly. Located in synaptonemal complex. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 12 and spermatogenic failure 15. Orthologous to human SYCE1 (synaptonemal complex central element protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 623.5), Kidney (RPKM 103.0) and 1 other tissue See more
    Orthologs
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    Genomic context

    See Syce1 in Genome Data Viewer
    Location:
    1q41
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (205281808..205292811, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (195852171..195863174, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (213523638..213534641, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA51 Neighboring gene cytochrome P450, family 2, subfamily e, polypeptide 1 Neighboring gene vacuole membrane protein 1, pseudogene 1 Neighboring gene Sec61 translocon subunit gamma, pseudogene 3 Neighboring gene urate (5-hydroxyiso-) hydrolase

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in synaptonemal complex assembly IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in central element ISO
    Inferred from Sequence Orthology
    more info
     
    located_in chromosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in synaptonemal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in synaptonemal complex IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    synaptonemal complex central element protein 1
    Names
    telomeric protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025058.2NP_001020229.2  synaptonemal complex central element protein 1

      See identical proteins and their annotated locations for NP_001020229.2

      Status: VALIDATED

      Source sequence(s)
      BC083907, CK596157
      UniProtKB/Swiss-Prot
      Q5XHZ2
      UniProtKB/TrEMBL
      A6HXJ5
      Related
      ENSRNOP00000035554.5, ENSRNOT00000033074.6
      Conserved Domains (1) summary
      pfam15233
      Location:54200
      SYCE1; Synaptonemal complex central element protein 1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      205281808..205292811 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)