Pabpn1l PABPN1 like [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Pabpn1lprovided by RGD
Official Full Name: PABPN1 likeprovided by RGD
Primary source: RGD:1562761
See related: EnsemblRapid:ENSRNOG00000029558 AllianceGenome:RGD:1562761
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Epabp2; Pabpnl1; RGD1562761
Summary: Predicted to enable poly(A) binding activity. Predicted to be involved in nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay. Predicted to act upstream of or within maternal-to-zygotic transition of gene expression; negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process; and negative regulation of protein ubiquitination. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Orthologous to human PABPN1L (PABPN1 like, cytoplasmic). [provided by Alliance of Genome Resources, Jan 2025]
Expression: Biased expression in Thymus (RPKM 2.6), Uterus (RPKM 0.8) and 8 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 19q12

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	19	NC_086037.1 (67578494..67581938, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	19	NC_051354.1 (50669965..50673409, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	19	NC_005118.4 (55430808..55434252, complement)

Chromosome 19 - NC_086037.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables RNA binding	ISO Inferred from Sequence Orthology more info
enables poly(A) binding	IBA Inferred from Biological aspect of Ancestor more info
enables poly(A) binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within maternal-to-zygotic transition of gene expression	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within negative regulation of protein ubiquitination	ISO Inferred from Sequence Orthology more info
involved_in nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: embryonic polyadenylate-binding protein 2

Names: Embryonic poly(A)-binding protein 2; Embryonic poly(A)-binding protein type II; ePABP-2; poly(A)binding protein nuclear 1-like; poly(A)binding protein nuclear-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001113779.1 → NP_001107251.1 embryonic polyadenylate-binding protein 2

See identical proteins and their annotated locations for NP_001107251.1

Status: PROVISIONAL

Source sequence(s)

BC158789

UniProtKB/Swiss-Prot

B0BNE4

UniProtKB/TrEMBL

A0A8L2QPA4, A6IZT6

Related

ENSRNOP00000050572.5, ENSRNOT00000045052.6

Conserved Domains (2) summary

COG0724
Location:129 → 223

RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

cl17169
Location:140 → 216

RRM_SF; RNA recognition motif (RRM) superfamily