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    Lekr1 leucine, glutamate and lysine rich 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361953, updated on 9-Dec-2024

    Summary

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    Symbol
    Lekr1provided by RGD
    Full Name
    leucine, glutamate and lysine rich 1provided by RGD
    Primary source
    RGD:1565425
    See related
    EnsemblRapid:ENSRNOG00000031247 AllianceGenome:RGD:1565425
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1562738; RGD1565425
    Summary
    Orthologous to human LEKR1 (leucine, glutamate and lysine rich 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 56.6), Brain (RPKM 18.4) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Lekr1 in Genome Data Viewer
    Location:
    2q31
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (152195003..152376389)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (149889615..150061167)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (157451912..157621908)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein L36A, pseudogene 11 Neighboring gene uncharacterized LOC134485623 Neighboring gene transfer RNA alanine (anticodon AGC) 101 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    protein LEKR1
    Names
    leucine-, glutamate- and lysine-rich protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001115029.2 → NP_001108501.2  protein LEKR1

      See identical proteins and their annotated locations for NP_001108501.2

      Status: PROVISIONAL

      Source sequence(s)
      BC158627, CA339992, JAXUCZ010000002
      UniProtKB/TrEMBL
      A0A8I6A518
      Related
      ENSRNOP00000087054.1, ENSRNOT00000098221.2
      Conserved Domains (1) summary
      cl19818
      Location:59 → 121
      DUF106; Integral membrane protein DUF106

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      152195003..152376389
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017590967.3 → XP_017446456.1  protein LEKR1 isoform X2

    2. XM_006232472.5 → XP_006232534.1  protein LEKR1 isoform X1

      Conserved Domains (1) summary
      pfam08764
      Location:436 → 578
      Coagulase; Staphylococcus aureus coagulase

    3. XM_039102618.2 → XP_038958546.1  protein LEKR1 isoform X6

      Conserved Domains (1) summary
      COG1196
      Location:130 → 428
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    4. XM_039102620.2 → XP_038958548.1  protein LEKR1 isoform X7

      Conserved Domains (1) summary
      COG1196
      Location:130 → 407
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    5. XM_039102621.2 → XP_038958549.1  protein LEKR1 isoform X8

      Conserved Domains (1) summary
      COG1196
      Location:130 → 420
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    6. XM_063282105.1 → XP_063138175.1  protein LEKR1 isoform X9

    7. XM_006232473.3 → XP_006232535.1  protein LEKR1 isoform X3

      See identical proteins and their annotated locations for XP_006232535.1

      UniProtKB/TrEMBL
      A0A8I6A518
      Conserved Domains (1) summary
      cl19818
      Location:59 → 121
      DUF106; Integral membrane protein DUF106

    8. XM_006232474.3 → XP_006232536.1  protein LEKR1 isoform X4

      See identical proteins and their annotated locations for XP_006232536.1

      Conserved Domains (1) summary
      cl19818
      Location:43 → 105
      DUF106; Integral membrane protein DUF106

    9. XM_039102616.2 → XP_038958544.1  protein LEKR1 isoform X5

      Conserved Domains (1) summary
      COG1196
      Location:136 → 494
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    10. XM_039102617.2 → XP_038958545.1  protein LEKR1 isoform X5

      Conserved Domains (1) summary
      COG1196
      Location:136 → 494
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    Nucleotide Protein Strain
    Heading Accession and Version

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