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    Zfp41 zinc finger protein 41 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100910508, updated on 4-Jan-2025

    Summary

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    Official Symbol
    Zfp41provided by RGD
    Official Full Name
    zinc finger protein 41provided by RGD
    Primary source
    RGD:1307587
    See related
    EnsemblRapid:ENSRNOG00000007489 AllianceGenome:RGD:1307587
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1307587
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZFP41 (ZFP41 zinc finger protein). [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Biased expression in Testes (RPKM 50.0), Spleen (RPKM 48.6) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zfp41 in Genome Data Viewer
    Location:
    7q34
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (109188010..109198546)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (107307303..107320164)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (116653618..116665414)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene lymphocyte antigen 6 family member H Neighboring gene glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 Neighboring gene GLI family zinc finger 4 Neighboring gene DNA topoisomerase I mitochondrial

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables sequence-specific double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 41 homolog
    Names
    GLI-Kruppel family member GLI4 (oncogene HKR4)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      109188010..109198546
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008765625.4 → XP_008763847.1  zinc finger protein 41 homolog

      See identical proteins and their annotated locations for XP_008763847.1

      UniProtKB/TrEMBL
      D3ZZK5
      Related
      ENSRNOP00000089045.1, ENSRNOT00000104546.2
      Conserved Domains (2) summary
      COG5189
      Location:111 → 191
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:117 → 137
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. XM_039080529.2 → XP_038936457.1  zinc finger protein 41 homolog

      UniProtKB/TrEMBL
      D3ZZK5
      Related
      ENSRNOP00000068439.1, ENSRNOT00000076606.3
      Conserved Domains (2) summary
      COG5189
      Location:111 → 191
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:117 → 137
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. XM_008765626.4 → XP_008763848.1  zinc finger protein 41 homolog

      See identical proteins and their annotated locations for XP_008763848.1

      UniProtKB/TrEMBL
      D3ZZK5
      Related
      ENSRNOP00000097386.1, ENSRNOT00000107500.2
      Conserved Domains (2) summary
      COG5189
      Location:111 → 191
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:117 → 137
      ZF_C2H2; C2H2 Zn finger [structural motif]

    4. XM_063264671.1 → XP_063120741.1  zinc finger protein 41 homolog

      UniProtKB/TrEMBL
      D3ZZK5

    5. XM_039080530.2 → XP_038936458.1  zinc finger protein 41 homolog

      UniProtKB/TrEMBL
      D3ZZK5
      Related
      ENSRNOP00000099994.1, ENSRNOT00000172546.1
      Conserved Domains (2) summary
      COG5189
      Location:111 → 191
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:117 → 137
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

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