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    Btnl9 butyrophilin-like 9 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 684480, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Btnl9provided by RGD
    Official Full Name
    butyrophilin-like 9provided by RGD
    Primary source
    RGD:1590287
    See related
    EnsemblRapid:ENSRNOG00000046377 AllianceGenome:RGD:1590287
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable signaling receptor binding activity. Predicted to be involved in T cell receptor signaling pathway and regulation of cytokine production. Predicted to be active in external side of plasma membrane. Orthologous to human BTNL9 (butyrophilin like 9). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 154.8), Muscle (RPKM 44.2) and 5 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Btnl9 in Genome Data Viewer
    Location:
    10q21
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (33967098..33990304, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (33466059..33489229, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (34424830..34443749, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 2 subfamily T member 26 Neighboring gene uncharacterized LOC120095085 Neighboring gene olfactory receptor family 2 subfamily M member 13 Neighboring gene zinc finger protein 62 Neighboring gene uncharacterized LOC134480779 Neighboring gene alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables signaling receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in T cell receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of cytokine production IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    butyrophilin-like 9; butyrophilin-like protein 9

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001430258.1 → NP_001417187.1  butyrophilin-like 9 isoform 1 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      M0R7E0

    2. NM_001430259.1 → NP_001417188.1  butyrophilin-like 9 isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      M0R7E0

    3. NM_001430260.1 → NP_001417189.1  butyrophilin-like 9 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      M0R7E0

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      33967098..33990304 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039087161.2 → XP_038943089.1  butyrophilin-like protein 9 isoform X3

      Conserved Domains (2) summary
      cd00096
      Location:40 → 43
      Ig; Ig strand A [structural motif]
      cl11960
      Location:40 → 151
      Ig; Immunoglobulin domain

    2. XM_039087163.2 → XP_038943091.1  butyrophilin-like protein 9 isoform X4

      UniProtKB/TrEMBL
      A6HDV5
      Conserved Domains (2) summary
      cd00096
      Location:40 → 43
      Ig; Ig strand A [structural motif]
      cl11960
      Location:40 → 151
      Ig; Immunoglobulin domain

    3. XM_039087158.2 → XP_038943086.1  butyrophilin-like protein 9 isoform X1

      Related
      ENSRNOP00000065366.4, ENSRNOT00000072081.5
      Conserved Domains (3) summary
      cd13733
      Location:326 → 500
      SPRY_PRY_C-I_1; PRY/SPRY domain in tripartite motif-containing (TRIM) proteins, including TRIM5, TRIM6, TRIM7, TRIM10, TRIM11, TRIM17, TRIM20, TRIM21, TRIM27, TRIM35, TRIM38, TRIM41, TRIM50, TRIM58, TRIM60, TRIM62, TRIM69, TRIM72, NF7 and bloodthirsty
      cd00096
      Location:40 → 43
      Ig; Ig strand A [structural motif]
      cl11960
      Location:40 → 151
      Ig; Immunoglobulin domain

    4. XM_039087159.2 → XP_038943087.1  butyrophilin-like protein 9 isoform X2

      Related
      ENSRNOP00000108032.1, ENSRNOT00000162386.1
      Conserved Domains (3) summary
      cd13733
      Location:283 → 457
      SPRY_PRY_C-I_1; PRY/SPRY domain in tripartite motif-containing (TRIM) proteins, including TRIM5, TRIM6, TRIM7, TRIM10, TRIM11, TRIM17, TRIM20, TRIM21, TRIM27, TRIM35, TRIM38, TRIM41, TRIM50, TRIM58, TRIM60, TRIM62, TRIM69, TRIM72, NF7 and bloodthirsty
      cd00096
      Location:40 → 43
      Ig; Ig strand A [structural motif]
      cl11960
      Location:40 → 151
      Ig; Immunoglobulin domain
    Nucleotide Protein Strain
    Heading Accession and Version

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