Bpifb2 BPI fold containing family B, member 2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Bpifb2provided by RGD
Official Full Name: BPI fold containing family B, member 2provided by RGD
Primary source: RGD:1310866
See related: EnsemblRapid:ENSRNOG00000012197 AllianceGenome:RGD:1310866
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Bpil1; Lplunc2
Summary: Predicted to enable lipid binding activity. Predicted to be located in extracellular region. Orthologous to human BPIFB2 (BPI fold containing family B member 2). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Restricted expression toward (RPKM 2.2) See more
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 3q41

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	3	NC_086021.1 (162818223..162837219)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	3	NC_051338.1 (142356990..142377053)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	3	NC_005102.4 (149358881..149377867)

Chromosome 3 - NC_086021.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables lipid binding	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: BPI fold-containing family B member 2

Names: bactericidal/permeability-increasing protein-like 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001106531.1 → NP_001100001.1 BPI fold-containing family B member 2 precursor

See identical proteins and their annotated locations for NP_001100001.1

Status: PROVISIONAL

Source sequence(s)

CH474050

UniProtKB/TrEMBL

A6KHW8, D4A5H4

Related

ENSRNOP00000016431.7, ENSRNOT00000016431.7

Conserved Domains (2) summary

pfam01273
Location:33 → 184

LBP_BPI_CETP; LBP / BPI / CETP family, N-terminal domain

cl00188
Location:255 → 456

BPI; BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086021.1 Reference GRCr8

Range

162818223..162837219

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039104607.2 → XP_038960535.1 BPI fold-containing family B member 2 isoform X1

UniProtKB/TrEMBL

D4A5H4

Conserved Domains (2) summary

pfam01273
Location:60 → 211

LBP_BPI_CETP; LBP / BPI / CETP family, N-terminal domain

cl00188
Location:282 → 483

BPI; BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative ...