U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    Tmt1b thiol methyltransferase 1B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 366792, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tmt1bprovided by RGD
    Official Full Name
    thiol methyltransferase 1Bprovided by RGD
    Primary source
    RGD:1305205
    See related
    EnsemblRapid:ENSRNOG00000007927 AllianceGenome:RGD:1305205
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Mettl7b; RGD1305205
    Summary
    Predicted to enable thiol S-methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in cytosol; endoplasmic reticulum membrane; and lipid droplet. Orthologous to human TMT1B (thiol methyltransferase 1B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 728.3), Kidney (RPKM 353.4) and 1 other tissue See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Tmt1b in Genome Data Viewer
    Location:
    7q11
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (1973334..1975980, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (1388876..1391526, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (3383876..3386522, complement)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120093529 Neighboring gene biogenesis of lysosomal organelles complex-1, subunit 1 Neighboring gene integrin subunit alpha 7 Neighboring gene olfactory receptor family 10 subfamily P member 22 Neighboring gene olfactory receptor family 10 subfamily P member 1 like 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Clone Names

    • MGC109041

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in methylation  
    Component Evidence Code Pubs
    located_in cytosol  
    located_in endoplasmic reticulum membrane  
    located_in lipid droplet  

    General protein information

    Preferred Names
    thiol S-methyltransferase TMT1B
    Names
    ALDI
    associated with lipid droplet protein 1
    methyltransferase like 7B
    methyltransferase-like protein 7B
    thiol S-methyltransferase METTL7B
    NP_001019447.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024276.1NP_001019447.1  thiol S-methyltransferase TMT1B precursor

      See identical proteins and their annotated locations for NP_001019447.1

      Status: PROVISIONAL

      Source sequence(s)
      BC092590
      UniProtKB/Swiss-Prot
      Q562C4
      UniProtKB/TrEMBL
      A6KSL1
      Related
      ENSRNOP00000010760.4, ENSRNOT00000010760.6
      Conserved Domains (1) summary
      pfam08241
      Location:75172
      Methyltransf_11; Methyltransferase domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      1973334..1975980 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    External link. Please review our privacy policy.