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    Cibar1 CBY1 interacting BAR domain containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 297903, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cibar1provided by RGD
    Official Full Name
    CBY1 interacting BAR domain containing 1provided by RGD
    Primary source
    RGD:1310681
    See related
    EnsemblRapid:ENSRNOG00000016338 AllianceGenome:RGD:1310681
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Fam92a; Fam92a1; RGD1310681
    Summary
    Predicted to enable phospholipid binding activity. Predicted to be involved in several processes, including inner mitochondrial membrane organization; membrane tubulation; and positive regulation of smoothened signaling pathway. Predicted to be located in several cellular components, including centriole; ciliary base; and mitochondrial crista. Predicted to be active in ciliary basal body and ciliary transition zone. Orthologous to human CIBAR1 (CBY1 interacting BAR domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 189.1), Brain (RPKM 135.7) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Cibar1 in Genome Data Viewer
    Location:
    5q13
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (30411325..30429770, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (25613993..25632440, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (25732457..25750953, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene RNA-binding protein 12B-A-like Neighboring gene transmembrane protein 67 Neighboring gene RNA binding motif protein 12B Neighboring gene uncharacterized LOC120102833 Neighboring gene triple QxxK/R motif containing Neighboring gene transfer RNA threonine (anticodon AGU) 10

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in cilium assembly  
    involved_in cilium assembly  
    involved_in inner mitochondrial membrane organization  
    involved_in inner mitochondrial membrane organization  
    involved_in limb morphogenesis  
    involved_in membrane organization  
    involved_in membrane tubulation  
    involved_in positive regulation of smoothened signaling pathway  
    Component Evidence Code Pubs
    located_in centriole  
    is_active_in ciliary basal body  
    located_in ciliary basal body  
    located_in ciliary base  
    is_active_in ciliary transition zone  
    located_in ciliary transition zone  
    located_in cilium  
    located_in cytoplasm  
    located_in cytoplasm  
    located_in mitochondrial crista  
    located_in mitochondrial inner membrane  
    located_in mitochondrial inner membrane  
    located_in mitochondrion  
    located_in nucleus  
    located_in nucleus  

    General protein information

    Preferred Names
    CBY1 interacting BAR domain containing 1; CBY1-interacting BAR domain-containing protein 1
    Names
    family with sequence similarity 92 member A
    family with sequence similarity 92, member A1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001431154.1NP_001418083.1  CBY1 interacting BAR domain containing 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/TrEMBL
      A6II83
    2. NM_001431155.1NP_001418084.1  CBY1 interacting BAR domain containing 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005
    3. NM_001431156.1NP_001418085.1  CBY1 interacting BAR domain containing 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      30411325..30429770 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063261262.1XP_063117332.1  CBY1-interacting BAR domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZZV0
      Related
      ENSRNOP00000084687.2, ENSRNOT00000115551.2
    2. XM_063261263.1XP_063117333.1  CBY1-interacting BAR domain-containing protein 1 isoform X2

      Related
      ENSRNOP00000022249.8, ENSRNOT00000022249.9
    3. XM_063261265.1XP_063117335.1  CBY1-interacting BAR domain-containing protein 1 isoform X4

    4. XM_002729463.7XP_002729509.2  CBY1-interacting BAR domain-containing protein 1 isoform X6

    5. XM_063261266.1XP_063117336.1  CBY1-interacting BAR domain-containing protein 1 isoform X5

    6. XM_063261264.1XP_063117334.1  CBY1-interacting BAR domain-containing protein 1 isoform X3

    7. XM_039110944.2XP_038966872.1  CBY1-interacting BAR domain-containing protein 1 isoform X7

      Conserved Domains (1) summary
      cl12013
      Location:78156
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    RNA

    1. XR_010051710.1 RNA Sequence

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