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    Bhlhe22 basic helix-loop-helix family, member e22 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 365748, updated on 9-Dec-2024

    Summary

    Official Symbol
    Bhlhe22provided by RGD
    Official Full Name
    basic helix-loop-helix family, member e22provided by RGD
    Primary source
    RGD:1305451
    See related
    EnsemblRapid:ENSRNOG00000021745 AllianceGenome:RGD:1305451
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Bhlhb5
    Summary
    Predicted to enable several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; E-box binding activity; and identical protein binding activity. Predicted to be involved in neuron differentiation; positive regulation of transcription by RNA polymerase II; and sensory organ development. Predicted to act upstream of or within cerebral cortex regionalization; negative regulation of DNA-templated transcription; and neuron differentiation. Predicted to be active in nucleus. Orthologous to human BHLHE22 (basic helix-loop-helix family member e22). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Bhlhe22 in Genome Data Viewer
    Location:
    2q24
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (102402622..102405732)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (100486400..100489510)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (102685513..102688624)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120100778 Neighboring gene microRNA 124-2 Neighboring gene pre-mRNA processing factor 38A, pseudogene 1 Neighboring gene cytochrome P450 family 7 subfamily B member 1 Neighboring gene ribosomal protein L30-like 3

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in nucleus  
    located_in nucleus  

    General protein information

    Preferred Names
    class E basic helix-loop-helix protein 22
    Names
    basic helix-loop-helix domain containing, class B5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108940.2NP_001102410.1  class E basic helix-loop-helix protein 22

      See identical proteins and their annotated locations for NP_001102410.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      A6IHA5, D4A287
      Related
      ENSRNOP00000038593.4, ENSRNOT00000033940.6
      Conserved Domains (1) summary
      smart00353
      Location:219273
      HLH; helix loop helix domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      102402622..102405732
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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