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    F3H flavanone 3-hydroxylase [ Glycine max (soybean) ]

    Gene ID: 732548, updated on 18-Aug-2023

    Summary

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    Gene symbol
    F3H
    Gene description
    flavanone 3-hydroxylase
    Locus tag
    GLYMA_02G048400v4
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Glycine max
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade; NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine; Glycine subgen. Soja
    Also known as
    F3H2
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    Genomic context

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    See F3H in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    104 current Glycine_max_v4.0 (GCF_000004515.6) 2 NC_016089.4 (4421727..4425294, complement)
    103 previous assembly Glycine_max_v2.1 (GCF_000004515.5) 2 NC_016089.3 (4440520..4444010, complement)

    Chromosome 2 - NC_016089.4Genomic Context describing neighboring genes Neighboring gene TSL-kinase interacting protein 1 Neighboring gene DNA-(apurinic or apyrimidinic site) endonuclease 2 Neighboring gene calcium-dependent protein kinase 28 Neighboring gene naringenin,2-oxoglutarate 3-dioxygenase Neighboring gene chromatin-remodeling ATPase INO80

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Accumulation of flavonols in response to ultraviolet-B irradiation in soybean is related to induction of flavanone 3-beta-hydroxylase and flavonol synthase. Kim BG, et al. Mol Cells, 2008 Apr 30. PMID 18414005
    2. Novel exon combinations generated by alternative splicing of gene fragments mobilized by a CACTA transposon in Glycine max. Zabala G, et al. BMC Plant Biol, 2007 Jul 14. PMID 17629935, Free PMC Article
    3. The wp mutation of Glycine max carries a gene-fragment-rich transposon of the CACTA superfamily. Zabala G, et al. Plant Cell, 2005 Oct. PMID 16141454, Free PMC Article
    4. Partial reconstruction of flavonoid and isoflavonoid biosynthesis in yeast using soybean type I and type II chalcone isomerases. Ralston L, et al. Plant Physiol, 2005 Apr. PMID 15778463, Free PMC Article
    5. Differential expression of isoflavone biosynthetic genes in soybean during water deficits. Gutierrez-Gonzalez JJ, et al. Plant Cell Physiol, 2010 Jun. PMID 20430761

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. GmF3H and GmFLS appear to be key enzymes in the biosynthesis of the ultraviolet-protectant, kaempferol.[F3H]
      Title: Accumulation of flavonols in response to ultraviolet-B irradiation in soybean is related to induction of flavanone 3-beta-hydroxylase and flavonol synthase.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    flavanone 3-hydroxylase
    NP_001236797.1
    XP_040862589.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001249868.3 → NP_001236797.1  flavanone 3-hydroxylase

      See identical proteins and their annotated locations for NP_001236797.1

      Status: VALIDATED

      Source sequence(s)
      ACUP04000463, AY595420
      UniProtKB/TrEMBL
      C1ICD6, Q53B69
      Conserved Domains (1) summary
      PLN02515
      Location:1 → 375
      PLN02515; naringenin,2-oxoglutarate 3-dioxygenase

    RefSeqs of Annotated Genomes: Glycine max Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Glycine_max_v4.0 Primary Assembly

    Genomic

    1. NC_016089.4 Reference Glycine_max_v4.0 Primary Assembly

      Range
      4421727..4425294 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_041006655.1 → XP_040862589.1  flavanone 3-hydroxylase isoform X1

      UniProtKB/TrEMBL
      C1ICD6, I1JCH6
      Conserved Domains (1) summary
      PLN02515
      Location:1 → 370
      PLN02515; naringenin,2-oxoglutarate 3-dioxygenase
    Nucleotide Protein
    Heading Accession and Version

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