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    Enkur enkurin, TRPC channel interacting protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 291354, updated on 9-Dec-2024

    Summary

    Official Symbol
    Enkurprovided by RGD
    Official Full Name
    enkurin, TRPC channel interacting proteinprovided by RGD
    Primary source
    RGD:1309839
    See related
    EnsemblRapid:ENSRNOG00000018631 AllianceGenome:RGD:1309839
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1309839
    Summary
    Predicted to enable calmodulin binding activity. Predicted to act upstream of or within establishment of left/right asymmetry and flagellated sperm motility. Predicted to be located in 9+0 motile cilium and sperm principal piece. Predicted to be active in acrosomal vesicle and axonemal B tubule inner sheath. Orthologous to human ENKUR (enkurin, TRPC channel interacting protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 267.6), Lung (RPKM 84.0) and 2 other tissues See more
    Orthologs
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    Genomic context

    See Enkur in Genome Data Viewer
    Location:
    17q12.3
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (88599057..88622668, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (83690105..83714756, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (88071794..88095444, complement)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene phosphoribosyl transferase domain containing 1 Neighboring gene uncharacterized LOC102550221 Neighboring gene uncharacterized LOC134482761 Neighboring gene threonine synthase-like 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables calmodulin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables calmodulin binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within establishment of left/right asymmetry ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in establishment of left/right asymmetry ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within flagellated sperm motility ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in flagellated sperm motility ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in 9+0 motile cilium ISO
    Inferred from Sequence Orthology
    more info
     
    located_in 9+2 motile cilium ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in acrosomal vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in acrosomal vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in axonemal B tubule inner sheath ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in axonemal microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in axonemal microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in sperm flagellum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in sperm flagellum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in sperm principal piece ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106126.1NP_001099596.1  enkurin

      See identical proteins and their annotated locations for NP_001099596.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473990
      UniProtKB/TrEMBL
      A6JMC3, D3ZWN6
      Related
      ENSRNOP00000025140.5, ENSRNOT00000025140.8
      Conserved Domains (1) summary
      pfam13864
      Location:152246
      Enkurin; Calmodulin-binding

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      88599057..88622668 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)