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    Mettl25 methyltransferase like 25 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 314798, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Mettl25provided by RGD
    Official Full Name
    methyltransferase like 25provided by RGD
    Primary source
    RGD:1310270
    See related
    EnsemblRapid:ENSRNOG00000027451 AllianceGenome:RGD:1310270
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1310270
    Summary
    Orthologous to human METTL25 (methyltransferase like 25). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 68.2), Lung (RPKM 61.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Mettl25 in Genome Data Viewer
    Location:
    7q21
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (42948934..43029610, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (41062276..41143056, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (47847812..47928495, complement)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene transmembrane O-mannosyltransferase targeting cadherins 2 Neighboring gene uncharacterized LOC120093578 Neighboring gene uncharacterized LOC134479681 Neighboring gene coiled-coil domain containing 59 Neighboring gene uncharacterized LOC134479682 Neighboring gene PTPRF interacting protein alpha 2 Neighboring gene sulfotransferase 1C2 pseudogene Neighboring gene acyl-CoA synthetase short-chain family member 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    probable methyltransferase-like protein 25
    Names
    methyltransferase-like protein 25

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108089.1 → NP_001101559.1  probable methyltransferase-like protein 25

      See identical proteins and their annotated locations for NP_001101559.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473960
      UniProtKB/TrEMBL
      A0A8I5Y618, B1WC27
      Related
      ENSRNOP00000029686.6, ENSRNOT00000038144.7
      Conserved Domains (1) summary
      cl17173
      Location:152 → 414
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      42948934..43029610 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039079101.2 → XP_038935029.2  probable methyltransferase-like protein 25 isoform X1

      UniProtKB/TrEMBL
      A0A8I6GC39, F6QFT3
      Related
      ENSRNOP00000084690.1, ENSRNOT00000094274.2

    2. XM_039079105.2 → XP_038935033.1  probable methyltransferase-like protein 25 isoform X4

      UniProtKB/TrEMBL
      A0A8I5ZNA4
      Conserved Domains (2) summary
      PTZ00098
      Location:50 → 95
      PTZ00098; phosphoethanolamine N-methyltransferase; Provisional
      cl17173
      Location:225 → 289
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

    3. XM_063263473.1 → XP_063119543.1  probable methyltransferase-like protein 25 isoform X5

    4. XM_063263472.1 → XP_063119542.1  probable methyltransferase-like protein 25 isoform X3

    5. XM_063263470.1 → XP_063119540.1  probable methyltransferase-like protein 25 isoform X2

    RNA

    1. XR_010052971.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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