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    Ccdc124 coiled-coil domain containing 124 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 290642, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ccdc124provided by RGD
    Official Full Name
    coiled-coil domain containing 124provided by RGD
    Primary source
    RGD:1310931
    See related
    EnsemblRapid:ENSRNOG00000018932 AllianceGenome:RGD:1310931
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1310931
    Summary
    Predicted to enable transcription coactivator activity. Predicted to be involved in transcription by RNA polymerase II. Predicted to be located in cytosol and plasma membrane. Predicted to be active in nucleus. Orthologous to human CCDC124 (coiled-coil domain containing 124). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 195.7), Heart (RPKM 127.3) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Ccdc124 in Genome Data Viewer
    Location:
    16p14
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (18600737..18606556)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (18566745..18572564)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (20317446..20323265)

    Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA68 Neighboring gene ribosomal protein L18A Neighboring gene solute carrier family 5 member 5 Neighboring gene uncharacterized LOC134482469 Neighboring gene potassium calcium-activated channel subfamily N member 1 Neighboring gene uncharacterized LOC134482468 Neighboring gene arrestin domain containing 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables transcription coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in positive regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in midbody IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    coiled-coil domain-containing protein 124

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106071.1NP_001099541.1  coiled-coil domain-containing protein 124

      See identical proteins and their annotated locations for NP_001099541.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474031
      UniProtKB/TrEMBL
      A6K9Y9, D3ZUL1
      Related
      ENSRNOP00000025626.4, ENSRNOT00000025626.7
      Conserved Domains (1) summary
      pfam06244
      Location:95206
      Ccdc124; Coiled-coil domain-containing protein 124

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086034.1 Reference GRCr8

      Range
      18600737..18606556
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006252867.5XP_006252929.1  coiled-coil domain-containing protein 124 isoform X1

      See identical proteins and their annotated locations for XP_006252929.1

      UniProtKB/TrEMBL
      A6K9Y9, D3ZUL1
      Conserved Domains (1) summary
      pfam06244
      Location:95206
      Ccdc124; Coiled-coil domain-containing protein 124