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    KLHL7 kelch like family member 7 [ Canis lupus familiaris (dog) ]

    Gene ID: 475255, updated on 17-Aug-2024

    Summary

    Official Symbol
    KLHL7provided by VGNC
    Official Full Name
    kelch like family member 7provided by VGNC
    Primary source
    VGNC:VGNC:42476
    See related
    Ensembl:ENSCAFG00845009174
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See KLHL7 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 14 NC_051818.1 (36717668..36784962)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 14 NC_006596.4 (36334667..36401129)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 14 NC_049274.1 (36839253..36905712)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 14 NC_049755.1 (36536704..36603149)

    Chromosome 14 - NC_051818.1Genomic Context describing neighboring genes Neighboring gene COP9 signalosome complex subunit 9 Neighboring gene uncharacterized LOC111098683 Neighboring gene nucleoporin 42 Neighboring gene glycoprotein nmb

    Genomic regions, transcripts, and products

    General protein information

    Preferred Names
    kelch-like protein 7
    Names
    kelch-like 7

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051818.1 Reference ROS_Cfam_1.0

      Range
      36717668..36784962
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038686713.1XP_038542641.1  kelch-like protein 7 isoform X2

      UniProtKB/TrEMBL
      A0A8C0QIP6, A0A8I3N740
      Related
      ENSCAFP00845012568.1, ENSCAFT00845016159.1
      Conserved Domains (4) summary
      PHA03098
      Location:7525
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:342386
      Kelch; KELCH repeat [structural motif]
      cd18237
      Location:1118
      BTB_POZ_KLHL7; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 7 (KLHL7)
      cd18447
      Location:110207
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
    2. XM_038686714.1XP_038542642.1  kelch-like protein 7 isoform X1

      UniProtKB/TrEMBL
      A0A8C0QIP6
      Conserved Domains (4) summary
      PHA03098
      Location:6507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:324368
      Kelch; KELCH repeat [structural motif]
      cd18447
      Location:92189
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
      cl38908
      Location:1100
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    3. XM_038686715.1XP_038542643.1  kelch-like protein 7 isoform X1

      UniProtKB/TrEMBL
      A0A8C0QIP6
      Conserved Domains (4) summary
      PHA03098
      Location:6507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:324368
      Kelch; KELCH repeat [structural motif]
      cd18447
      Location:92189
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
      cl38908
      Location:1100
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049274.1 Alternate UMICH_Zoey_3.1

      Range
      36839253..36905712
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038494813.1XP_038350741.1  kelch-like protein 7 isoform X1

      Conserved Domains (4) summary
      PHA03098
      Location:6507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:324368
      Kelch; KELCH repeat [structural motif]
      cd18447
      Location:92189
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
      cl38908
      Location:1100
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    2. XM_038494815.1XP_038350743.1  kelch-like protein 7 isoform X1

      Conserved Domains (4) summary
      PHA03098
      Location:6507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:324368
      Kelch; KELCH repeat [structural motif]
      cd18447
      Location:92189
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
      cl38908
      Location:1100
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    3. XM_038494811.1XP_038350739.1  kelch-like protein 7 isoform X1

      Conserved Domains (4) summary
      PHA03098
      Location:6507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:324368
      Kelch; KELCH repeat [structural motif]
      cd18447
      Location:92189
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
      cl38908
      Location:1100
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    4. XM_038494812.1XP_038350740.1  kelch-like protein 7 isoform X1

      Conserved Domains (4) summary
      PHA03098
      Location:6507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:324368
      Kelch; KELCH repeat [structural motif]
      cd18447
      Location:92189
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
      cl38908
      Location:1100
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    5. XM_038494810.1XP_038350738.1  kelch-like protein 7 isoform X3

      Conserved Domains (4) summary
      PHA03098
      Location:37555
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:372416
      Kelch; KELCH repeat [structural motif]
      cd18237
      Location:23148
      BTB_POZ_KLHL7; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 7 (KLHL7)
      cd18447
      Location:140237
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
    6. XM_038494814.1XP_038350742.1  kelch-like protein 7 isoform X1

      Conserved Domains (4) summary
      PHA03098
      Location:6507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:324368
      Kelch; KELCH repeat [structural motif]
      cd18447
      Location:92189
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
      cl38908
      Location:1100
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    7. XM_038494818.1XP_038350746.1  kelch-like protein 7 isoform X1

      Conserved Domains (4) summary
      PHA03098
      Location:6507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:324368
      Kelch; KELCH repeat [structural motif]
      cd18447
      Location:92189
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
      cl38908
      Location:1100
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    8. XM_038494817.1XP_038350745.1  kelch-like protein 7 isoform X1

      Conserved Domains (4) summary
      PHA03098
      Location:6507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:324368
      Kelch; KELCH repeat [structural motif]
      cd18447
      Location:92189
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
      cl38908
      Location:1100
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    9. XM_038494816.1XP_038350744.1  kelch-like protein 7 isoform X1

      Conserved Domains (4) summary
      PHA03098
      Location:6507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:324368
      Kelch; KELCH repeat [structural motif]
      cd18447
      Location:92189
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
      cl38908
      Location:1100
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    10. XM_038494819.1XP_038350747.1  kelch-like protein 7 isoform X1

      Conserved Domains (4) summary
      PHA03098
      Location:6507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:324368
      Kelch; KELCH repeat [structural motif]
      cd18447
      Location:92189
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
      cl38908
      Location:1100
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049755.1 Alternate UNSW_CanFamBas_1.0

      Range
      36536704..36603149
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038621029.1XP_038476957.1  kelch-like protein 7 isoform X1

      Conserved Domains (4) summary
      PHA03098
      Location:6507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:324368
      Kelch; KELCH repeat [structural motif]
      cd18447
      Location:92189
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
      cl38908
      Location:1100
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    2. XM_038621031.1XP_038476959.1  kelch-like protein 7 isoform X1

      Conserved Domains (4) summary
      PHA03098
      Location:6507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:324368
      Kelch; KELCH repeat [structural motif]
      cd18447
      Location:92189
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
      cl38908
      Location:1100
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    3. XM_038621027.1XP_038476955.1  kelch-like protein 7 isoform X1

      Conserved Domains (4) summary
      PHA03098
      Location:6507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:324368
      Kelch; KELCH repeat [structural motif]
      cd18447
      Location:92189
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
      cl38908
      Location:1100
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    4. XM_038621028.1XP_038476956.1  kelch-like protein 7 isoform X1

      Conserved Domains (4) summary
      PHA03098
      Location:6507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:324368
      Kelch; KELCH repeat [structural motif]
      cd18447
      Location:92189
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
      cl38908
      Location:1100
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    5. XM_038621026.1XP_038476954.1  kelch-like protein 7 isoform X4

      Conserved Domains (4) summary
      PHA03098
      Location:37555
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:372416
      Kelch; KELCH repeat [structural motif]
      cd18237
      Location:23148
      BTB_POZ_KLHL7; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 7 (KLHL7)
      cd18447
      Location:140237
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
    6. XM_038621030.1XP_038476958.1  kelch-like protein 7 isoform X1

      Conserved Domains (4) summary
      PHA03098
      Location:6507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:324368
      Kelch; KELCH repeat [structural motif]
      cd18447
      Location:92189
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
      cl38908
      Location:1100
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    7. XM_038621034.1XP_038476962.1  kelch-like protein 7 isoform X1

      Conserved Domains (4) summary
      PHA03098
      Location:6507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:324368
      Kelch; KELCH repeat [structural motif]
      cd18447
      Location:92189
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
      cl38908
      Location:1100
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    8. XM_038621033.1XP_038476961.1  kelch-like protein 7 isoform X1

      Conserved Domains (4) summary
      PHA03098
      Location:6507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:324368
      Kelch; KELCH repeat [structural motif]
      cd18447
      Location:92189
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
      cl38908
      Location:1100
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    9. XM_038621032.1XP_038476960.1  kelch-like protein 7 isoform X1

      Conserved Domains (4) summary
      PHA03098
      Location:6507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:324368
      Kelch; KELCH repeat [structural motif]
      cd18447
      Location:92189
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
      cl38908
      Location:1100
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    10. XM_038621035.1XP_038476963.1  kelch-like protein 7 isoform X1

      Conserved Domains (4) summary
      PHA03098
      Location:6507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:324368
      Kelch; KELCH repeat [structural motif]
      cd18447
      Location:92189
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
      cl38908
      Location:1100
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006596.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      36334667..36401129
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038446015.1XP_038301943.1  kelch-like protein 7 isoform X1

      UniProtKB/TrEMBL
      A0A8C0QIP6
      Conserved Domains (4) summary
      PHA03098
      Location:6507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:324368
      Kelch; KELCH repeat [structural motif]
      cd18447
      Location:92189
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
      cl38908
      Location:1100
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    2. XM_038446035.1XP_038301963.1  kelch-like protein 7 isoform X1

      UniProtKB/TrEMBL
      A0A8C0QIP6
      Conserved Domains (4) summary
      PHA03098
      Location:6507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:324368
      Kelch; KELCH repeat [structural motif]
      cd18447
      Location:92189
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
      cl38908
      Location:1100
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    3. XM_038446000.1XP_038301928.1  kelch-like protein 7 isoform X1

      UniProtKB/TrEMBL
      A0A8C0QIP6
      Conserved Domains (4) summary
      PHA03098
      Location:6507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:324368
      Kelch; KELCH repeat [structural motif]
      cd18447
      Location:92189
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
      cl38908
      Location:1100
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    4. XM_038446011.1XP_038301939.1  kelch-like protein 7 isoform X1

      UniProtKB/TrEMBL
      A0A8C0QIP6
      Conserved Domains (4) summary
      PHA03098
      Location:6507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:324368
      Kelch; KELCH repeat [structural motif]
      cd18447
      Location:92189
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
      cl38908
      Location:1100
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    5. XM_038445997.1XP_038301925.1  kelch-like protein 7 isoform X5

      UniProtKB/TrEMBL
      A0A8C0JQF1, A0A8C0PIU6, A0A8C0QIP6, A0A8P0N5R4
      Conserved Domains (4) summary
      PHA03098
      Location:37555
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:372416
      Kelch; KELCH repeat [structural motif]
      cd18237
      Location:23148
      BTB_POZ_KLHL7; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 7 (KLHL7)
      cd18447
      Location:140237
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
    6. XM_022427469.2XP_022283177.1  kelch-like protein 7 isoform X1

      UniProtKB/TrEMBL
      A0A8C0QIP6
      Conserved Domains (4) summary
      PHA03098
      Location:6507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:324368
      Kelch; KELCH repeat [structural motif]
      cd18447
      Location:92189
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
      cl38908
      Location:1100
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    7. XM_532490.7XP_532490.4  kelch-like protein 7 isoform X1

      See identical proteins and their annotated locations for XP_532490.4

      UniProtKB/TrEMBL
      A0A8C0QIP6
      Conserved Domains (4) summary
      PHA03098
      Location:6507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:324368
      Kelch; KELCH repeat [structural motif]
      cd18447
      Location:92189
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
      cl38908
      Location:1100
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    8. XM_005628620.3XP_005628677.1  kelch-like protein 7 isoform X1

      See identical proteins and their annotated locations for XP_005628677.1

      UniProtKB/TrEMBL
      A0A8C0QIP6
      Conserved Domains (4) summary
      PHA03098
      Location:6507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:324368
      Kelch; KELCH repeat [structural motif]
      cd18447
      Location:92189
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
      cl38908
      Location:1100
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    9. XM_022427471.2XP_022283179.1  kelch-like protein 7 isoform X1

      UniProtKB/TrEMBL
      A0A8C0QIP6
      Conserved Domains (4) summary
      PHA03098
      Location:6507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:324368
      Kelch; KELCH repeat [structural motif]
      cd18447
      Location:92189
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
      cl38908
      Location:1100
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    10. XM_022427472.2XP_022283180.1  kelch-like protein 7 isoform X1

      UniProtKB/TrEMBL
      A0A8C0QIP6
      Conserved Domains (4) summary
      PHA03098
      Location:6507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:324368
      Kelch; KELCH repeat [structural motif]
      cd18447
      Location:92189
      BACK_KLHL7; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 7 (KLHL7)
      cl38908
      Location:1100
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily