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    Card19 caspase recruitment domain family, member 19 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361224, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Card19provided by RGD
    Official Full Name
    caspase recruitment domain family, member 19provided by RGD
    Primary source
    RGD:1306058
    See related
    EnsemblRapid:ENSRNOG00000016560 AllianceGenome:RGD:1306058
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Bincard; RGD1306058
    Summary
    Predicted to be located in membrane. Predicted to be active in mitochondrion. Orthologous to human CARD19 (caspase recruitment domain family member 19). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 82.5), Adrenal (RPKM 64.0) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Card19 in Genome Data Viewer
    Location:
    17p14
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (15638973..15651720)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (15432632..15445317)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (15845920..15858750)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene FYVE, RhoGEF and PH domain containing 3 Neighboring gene uncharacterized LOC134482823 Neighboring gene sushi domain containing 3 Neighboring gene ninjurin 1 Neighboring gene WNK lysine deficient protein kinase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. p38α MAPK proximity assay reveals a regulatory mechanism of alternative splicing in cardiomyocytes. Dumont AA, et al. Biochim Biophys Acta Mol Cell Res, 2019 Dec. PMID 31505169
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    caspase recruitment domain-containing protein 19
    Names
    Bcl10-interacting protein with Card
    bcl10-interacting CARD protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001419150.1 → NP_001406079.1  caspase recruitment domain-containing protein 19 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/TrEMBL
      A6J6X4, D3ZPP9
      Related
      ENSRNOP00000022203.5, ENSRNOT00000022203.7

    2. NM_001419151.1 → NP_001406080.1  caspase recruitment domain-containing protein 19 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/TrEMBL
      A6J6X5
      Related
      ENSRNOP00000090268.2, ENSRNOT00000108600.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      15638973..15651720
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063276569.1 → XP_063132639.1  caspase recruitment domain-containing protein 19 isoform X1

      UniProtKB/TrEMBL
      A0A8I6AAF1

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001134572.1: Suppressed sequence

      Description
      NM_001134572.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

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