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    Ccdc172 coiled-coil domain containing 172 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361776, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ccdc172provided by RGD
    Official Full Name
    coiled-coil domain containing 172provided by RGD
    Primary source
    RGD:1359412
    See related
    EnsemblRapid:ENSRNOG00000017656 AllianceGenome:RGD:1359412
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Located in sperm midpiece. Orthologous to human CCDC172 (coiled-coil domain containing 172). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 37.5) and Thymus (RPKM 12.1) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ccdc172 in Genome Data Viewer
    Location:
    1q55
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (267615341..267661568)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (257629188..257682373)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (279633655..279699234)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102556644 Neighboring gene GDNF family receptor alpha 1 Neighboring gene transfer RNA proline (anticodon GGG) 2 Neighboring gene pancreatic lipase Neighboring gene pancreatic lipase-related protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning and subcellular localization of Tektin2-binding protein 1 (Ccdc 172) in rat spermatozoa. Yamaguchi A, et al. J Histochem Cytochem, 2014 Apr. PMID 24394471, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in sperm midpiece IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    coiled-coil domain-containing protein 172
    Names
    TEKT2-binding protein 1
    UPF0628 protein C10orf96 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014169.2 → NP_001014191.1  coiled-coil domain-containing protein 172

      See identical proteins and their annotated locations for NP_001014191.1

      Status: VALIDATED

      Source sequence(s)
      BC079324, CV104909
      UniProtKB/Swiss-Prot
      Q6AXT4
      Related
      ENSRNOP00000071660.3, ENSRNOT00000091669.3
      Conserved Domains (1) summary
      TIGR02168
      Location:17 → 208
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      267615341..267661568
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039084726.2 → XP_038940654.1  coiled-coil domain-containing protein 172 isoform X1

      Conserved Domains (1) summary
      TIGR02168
      Location:17 → 251
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    2. XM_039084731.2 → XP_038940659.1  coiled-coil domain-containing protein 172 isoform X2

      UniProtKB/TrEMBL
      A0A8L2R556
      Related
      ENSRNOP00000105984.1, ENSRNOT00000150717.1
      Conserved Domains (1) summary
      TIGR02168
      Location:17 → 250
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    3. XM_039084738.2 → XP_038940666.1  coiled-coil domain-containing protein 172 isoform X5

      Conserved Domains (1) summary
      TIGR02168
      Location:17 → 208
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    4. XM_039084735.2 → XP_038940663.1  coiled-coil domain-containing protein 172 isoform X3

      Conserved Domains (1) summary
      NF033930
      Location:14 → 214
      pneumo_PspA; pneumococcal surface protein A

    5. XM_063268852.1 → XP_063124922.1  coiled-coil domain-containing protein 172 isoform X4

    6. XM_063268857.1 → XP_063124927.1  coiled-coil domain-containing protein 172 isoform X6

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6AXT4.1 GenPept UniProtKB/Swiss-Prot:Q6AXT4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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