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    Klhdc9 kelch domain containing 9 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 360878, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Klhdc9provided by RGD
    Official Full Name
    kelch domain containing 9provided by RGD
    Primary source
    RGD:1561025
    See related
    EnsemblRapid:ENSRNOG00000004022 AllianceGenome:RGD:1561025
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1561025
    Summary
    Predicted to enable cyclin binding activity. Orthologous to human KLHDC9 (kelch domain containing 9). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 17.6), Kidney (RPKM 15.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Klhdc9 in Genome Data Viewer
    Location:
    13q24
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (86323004..86326237, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (83790390..83794080, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (89742750..89746254, complement)

    Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene death effector domain-containing Neighboring gene nitrilase 1 Neighboring gene prefoldin subunit 2 Neighboring gene nectin cell adhesion molecule 4 Neighboring gene Rho GTPase activating protein 30

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Identification of interaction partners and substrates of the cyclin A1-CDK2 complex. Diederichs S, et al. J Biol Chem, 2004 Aug 6. PMID 15159402
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables cyclin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables cyclin binding ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    kelch domain-containing protein 9

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108350.2 → NP_001101820.1  kelch domain-containing protein 9

      See identical proteins and their annotated locations for NP_001101820.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000013
      UniProtKB/TrEMBL
      A6JFY8, D3ZDT0
      Related
      ENSRNOP00000005352.5, ENSRNOT00000005352.7
      Conserved Domains (3) summary
      smart00612
      Location:94 → 137
      Kelch; Kelch domain
      sd00038
      Location:28 → 76
      Kelch; KELCH repeat [structural motif]
      pfam13854
      Location:256 → 295
      Kelch_5; Kelch motif

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086031.1 Reference GRCr8

      Range
      86323004..86326237 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039090918.2 → XP_038946846.1  kelch domain-containing protein 9 isoform X1

      Conserved Domains (3) summary
      sd00038
      Location:52 → 110
      Kelch; KELCH repeat [structural motif]
      pfam13854
      Location:121 → 160
      Kelch_5; Kelch motif
      pfam15492
      Location:39 → 91
      Nbas_N; Neuroblastoma-amplified sequence, N terminal

    2. XM_039090919.2 → XP_038946847.1  kelch domain-containing protein 9 isoform X2

      Conserved Domains (2) summary
      smart00612
      Location:94 → 137
      Kelch; Kelch domain
      sd00038
      Location:28 → 76
      Kelch; KELCH repeat [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

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