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    Zfp385d zinc finger protein 385D [ Rattus norvegicus (Norway rat) ]

    Gene ID: 305691, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp385dprovided by RGD
    Official Full Name
    zinc finger protein 385Dprovided by RGD
    Primary source
    RGD:1359606
    See related
    EnsemblRapid:ENSRNOG00000014661 AllianceGenome:RGD:1359606
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Znf385d
    Summary
    Predicted to enable sequence-specific double-stranded DNA binding activity. Predicted to be active in nucleus. Orthologous to human ZNF385D (zinc finger protein 385D). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 27.7), Testes (RPKM 18.8) and 7 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Zfp385d in Genome Data Viewer
    Location:
    15p16
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (7473431..7854364, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (5040182..5849975, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (6200825..7249168, complement)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene proteasome 20S subunit beta 3, pseudogene 8 Neighboring gene Tu translation elongation factor, mitochondrial, pseudogene 2 Neighboring gene SFT2 domain containing 2, pseudogene 1 Neighboring gene igE-binding protein-like Neighboring gene small nucleolar RNA SNORA17

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 385D
    Names
    zinc finger protein 659

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013992.1 → NP_001014014.1  zinc finger protein 385D

      See identical proteins and their annotated locations for NP_001014014.1

      Status: PROVISIONAL

      Source sequence(s)
      BC079278
      UniProtKB/Swiss-Prot
      Q6AXX3
      UniProtKB/TrEMBL
      F1LSB4
      Related
      ENSRNOP00000035178.6, ENSRNOT00000038449.6
      Conserved Domains (2) summary
      sd00020
      Location:206 → 268
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam12874
      Location:268 → 291
      zf-met; Zinc-finger of C2H2 type

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      7473431..7854364 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063274196.1 → XP_063130266.1  zinc finger protein 385D isoform X3

      UniProtKB/TrEMBL
      A0A8I6A5X7, F1LSB4
      Related
      ENSRNOP00000087489.1, ENSRNOT00000102905.2

    2. XM_039093237.2 → XP_038949165.1  zinc finger protein 385D isoform X2

      UniProtKB/TrEMBL
      A6K027
      Conserved Domains (2) summary
      sd00020
      Location:171 → 233
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam12874
      Location:232 → 256
      zf-met; Zinc-finger of C2H2 type

    3. XM_039093239.2 → XP_038949167.1  zinc finger protein 385D isoform X4

      UniProtKB/TrEMBL
      A6K027
      Related
      ENSRNOP00000111399.1, ENSRNOT00000161916.1
      Conserved Domains (2) summary
      sd00020
      Location:151 → 213
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam12874
      Location:212 → 236
      zf-met; Zinc-finger of C2H2 type

    4. XM_039093236.2 → XP_038949164.1  zinc finger protein 385D isoform X2

      UniProtKB/TrEMBL
      A6K027
      Conserved Domains (2) summary
      sd00020
      Location:171 → 233
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam12874
      Location:232 → 256
      zf-met; Zinc-finger of C2H2 type

    5. XM_017599647.3 → XP_017455136.1  zinc finger protein 385D isoform X1

      UniProtKB/TrEMBL
      F1LSB4
      Related
      ENSRNOP00000083760.1, ENSRNOT00000112614.2

    6. XM_063274197.1 → XP_063130267.1  zinc finger protein 385D isoform X5

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6AXX3.1 GenPept UniProtKB/Swiss-Prot:Q6AXX3

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