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    Slc25a30 solute carrier family 25, member 30 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361074, updated on 9-Dec-2024

    Summary

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    Symbol
    Slc25a30provided by RGD
    Full Name
    solute carrier family 25, member 30provided by RGD
    Primary source
    RGD:1359702
    See related
    EnsemblRapid:ENSRNOG00000001052 AllianceGenome:RGD:1359702
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable solute:inorganic anion antiporter activity. Predicted to be involved in inorganic anion transport. Predicted to be located in mitochondrion. Orthologous to human SLC25A30 (solute carrier family 25 member 30). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 602.1), Kidney (RPKM 540.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Slc25a30 in Genome Data Viewer
    Location:
    15q11
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (57486346..57508981, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (51076998..51099613, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (57811612..57834173, complement)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene siah E3 ubiquitin protein ligase family member 3 Neighboring gene uncharacterized LOC120097040 Neighboring gene chibby family member 2 Neighboring gene GABA type A receptor associated protein like 2, pseudogene 2 Neighboring gene glutamate-rich 6B Neighboring gene component of oligomeric golgi complex 3 Neighboring gene uncharacterized LOC102552389 Neighboring gene small nucleolar RNA, H/ACA box 31 Neighboring gene tumor protein, translationally-controlled 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. A new renal mitochondrial carrier, KMCP1, is up-regulated during tubular cell regeneration and induction of antioxidant enzymes. Haguenauer A, et al. J Biol Chem, 2005 Jun 10. PMID 15809292
    2. Noncanonical and canonical splice sites: a novel mutation at the rare noncanonical splice-donor cut site (IVS4+1A>G) of SEDL causes variable splicing isoforms in X-linked spondyloepiphyseal dysplasia tarda. Xiong F, et al. Eur J Hum Genet, 2009 Apr. PMID 19002213, Free PMC Article
    3. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables solute:inorganic anion antiporter activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables solute:inorganic anion antiporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in inorganic anion transport ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in inorganic anion transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    kidney mitochondrial carrier protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013187.2 → NP_001013205.1  kidney mitochondrial carrier protein 1

      See identical proteins and their annotated locations for NP_001013205.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000015
      UniProtKB/Swiss-Prot
      Q5PQM9
      UniProtKB/TrEMBL
      F1LR53
      Conserved Domains (2) summary
      PTZ00169
      Location:9 → 289
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
      pfam00153
      Location:199 → 289
      Mito_carr; Mitochondrial carrier protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      57486346..57508981 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008770873.4 → XP_008769095.2  kidney mitochondrial carrier protein 1 isoform X1

      UniProtKB/Swiss-Prot
      Q5PQM9
      UniProtKB/TrEMBL
      F1LR53
      Conserved Domains (2) summary
      PTZ00169
      Location:9 → 289
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
      pfam00153
      Location:199 → 289
      Mito_carr; Mitochondrial carrier protein

    2. XM_063274438.1 → XP_063130508.1  kidney mitochondrial carrier protein 1 isoform X1

      UniProtKB/Swiss-Prot
      Q5PQM9
      UniProtKB/TrEMBL
      F1LR53
      Related
      ENSRNOP00000097957.1, ENSRNOT00000104191.2
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5PQM9.1 GenPept UniProtKB/Swiss-Prot:Q5PQM9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials