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    Iqca1 IQ motif containing with AAA domain 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 316616, updated on 9-Dec-2024

    Summary

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    Symbol
    Iqca1provided by RGD
    Full Name
    IQ motif containing with AAA domain 1provided by RGD
    Primary source
    RGD:1305311
    See related
    EnsemblRapid:ENSRNOG00000019592 AllianceGenome:RGD:1305311
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Iqca; RGD1305311
    Summary
    Predicted to enable ATP binding activity and ATP hydrolysis activity. Orthologous to human IQCA1 (IQ motif containing with AAA domain 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 33.3), Lung (RPKM 16.9) and 3 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Iqca1 in Genome Data Viewer
    Location:
    9q36
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (98074389..98190233, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (90626735..90742563, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (97190240..97298760, complement)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene gastrulation brain homeobox 2 Neighboring gene ankyrin repeat and SOCS box-containing 18 Neighboring gene uncharacterized LOC102554789 Neighboring gene uncharacterized LOC134480407 Neighboring gene uncharacterized LOC134480408 Neighboring gene atypical chemokine receptor 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    IQ motif containing with AAA domain 1; dynein regulatory complex protein 11
    Names
    IQ and AAA domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001431271.1 → NP_001418200.1  IQ motif containing with AAA domain 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      F1LX47, F1M7Z2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      98074389..98190233 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017596905.3 → XP_017452394.2  dynein regulatory complex protein 11 isoform X1

      Related
      ENSRNOP00000053565.6, ENSRNOT00000056724.7
      Conserved Domains (2) summary
      TIGR01243
      Location:420 → 758
      CDC48; AAA family ATPase, CDC48 subfamily
      cl38936
      Location:549 → 708
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    2. XM_039084725.2 → XP_038940653.1  dynein regulatory complex protein 11 isoform X2

      Conserved Domains (2) summary
      TIGR01243
      Location:420 → 618
      CDC48; AAA family ATPase, CDC48 subfamily
      cl38936
      Location:549 → 629
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    Nucleotide Protein Strain
    Heading Accession and Version

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