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    Sult2a6 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 6 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 24902, updated on 9-Dec-2024

    Summary

    Official Symbol
    Sult2a6provided by RGD
    Official Full Name
    sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 6provided by RGD
    Primary source
    RGD:3727
    See related
    EnsemblRapid:ENSRNOG00000047986 AllianceGenome:RGD:3727
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    ST-41; ST2A6; Smp2a; St2a2; BAST I; RATSMP2A; RATSMP2B; Sult2al1; Sult2a4l1
    Summary
    Predicted to enable sulfotransferase activity. Predicted to be involved in sulfation. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human SULT2A1 (sulfotransferase family 2A member 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 10922.3) See more
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    Genomic context

    See Sult2a6 in Genome Data Viewer
    Location:
    1q21
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (84046685..84097808, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (74911097..74962239, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (76529121..76722965, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene sulfotransferase family 2A member 1, pseudogene 1 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene nucleolin, pseudogene 5 Neighboring gene nucleolin, pseudogene 3 Neighboring gene alcohol sulfotransferase-like Neighboring gene U6 spliceosomal RNA Neighboring gene transfer RNA glycine (anticodon ACC) 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables alcohol sulfotransferase activity  
    enables bile-salt sulfotransferase activity  
    enables sulfotransferase activity  
    enables sulfotransferase activity  
    Process Evidence Code Pubs
    involved_in biological_process  
    involved_in steroid metabolic process  
    involved_in sulfation  
    Component Evidence Code Pubs
    is_active_in cytoplasm  
    located_in cytoplasm  
    located_in cytosol  

    General protein information

    Preferred Names
    sulfotransferase 2A6
    Names
    AD-ST
    ST-40
    STA
    Sult2al1, sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring-like 1
    alcohol sulfotransferase A
    androsterone-sulfating sulfotransferase
    bile acid:3'phosphoadenosine-5'phosphosulfate:sulfotransferase I
    hydroxysteroid sulfotransferase A
    senescence marker protein 2A gene, exons 1 and 2
    sulfotransferase 2A2
    sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 4-like 1
    sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring-like 1
    NP_036827.3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_012695.4NP_036827.3  sulfotransferase 2A6

      See identical proteins and their annotated locations for NP_036827.3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/Swiss-Prot
      P22789, Q63551
      UniProtKB/TrEMBL
      F1M7G5
      Related
      ENSRNOP00000045076.5, ENSRNOT00000052129.4
      Conserved Domains (1) summary
      pfam00685
      Location:33277
      Sulfotransfer_1; Sulfotransferase domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      84046685..84097808 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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