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    Zmynd10 zinc finger, MYND-type containing 10 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 363139, updated on 9-Dec-2024

    Summary

    Official Symbol
    Zmynd10provided by RGD
    Official Full Name
    zinc finger, MYND-type containing 10provided by RGD
    Primary source
    RGD:1303250
    See related
    EnsemblRapid:ENSRNOG00000021602 AllianceGenome:RGD:1303250
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable molecular adaptor activity and protein folding chaperone. Predicted to be involved in cilium assembly and positive regulation of motile cilium assembly. Predicted to act upstream of or within cilium movement; protein folding; and protein localization to cilium. Located in centriolar satellite. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 22. Orthologous to human ZMYND10 (zinc finger MYND-type containing 10). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 229.1), Lung (RPKM 76.3) and 7 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Zmynd10 in Genome Data Viewer
    Location:
    8q32
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (117098790..117103387)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (108220386..108224745)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (116302513..116306871)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene cytochrome b561 family, member D2 Neighboring gene NPR2-like, GATOR1 complex subunit Neighboring gene Ras association domain family member 1 Neighboring gene tumor suppressor 2, mitochondrial calcium regulator

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Clone Names

    • MGC94352

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables molecular adaptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein folding chaperone ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within cilium movement ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in inner dynein arm assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within inner dynein arm assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in inner dynein arm assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in inner dynein arm assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in motile cilium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within motile cilium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in motile cilium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in motile cilium assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in outer dynein arm assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within outer dynein arm assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in outer dynein arm assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in outer dynein arm assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of motile cilium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of motile cilium assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within protein folding ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within protein localization to cilium ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in apical plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in apical plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in centriolar satellite IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in centriolar satellite IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in dynein axonemal particle ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    zinc finger MYND domain-containing protein 10
    Names
    zinc finger, MYND domain-containing 10

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004284.1NP_001004284.1  zinc finger MYND domain-containing protein 10

      See identical proteins and their annotated locations for NP_001004284.1

      Status: PROVISIONAL

      Source sequence(s)
      BC079255
      UniProtKB/Swiss-Prot
      Q6AXZ5
      UniProtKB/TrEMBL
      A0A8I6A1M9
      Related
      ENSRNOP00000031055.3, ENSRNOT00000039258.5
      Conserved Domains (1) summary
      pfam01753
      Location:394430
      zf-MYND; MYND finger

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      117098790..117103387
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_010053996.1 RNA Sequence