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    Tma16 translation machinery associated 16 homolog [ Rattus norvegicus (Norway rat) ]

    Gene ID: 290686, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tma16provided by RGD
    Official Full Name
    translation machinery associated 16 homologprovided by RGD
    Primary source
    RGD:1305222
    See related
    EnsemblRapid:ENSRNOG00000089425 AllianceGenome:RGD:1305222
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1305222
    Summary
    Predicted to enable preribosome binding activity. Predicted to be involved in ribosomal large subunit biogenesis. Predicted to be located in nucleolus and nucleoplasm. Predicted to be active in nucleus. Orthologous to human TMA16 (translation machinery associated 16 homolog). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 32.7), Brain (RPKM 30.6) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Tma16 in Genome Data Viewer
    Location:
    16p14
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (28003002..28021875)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (23236686..23252706)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (24978429..24997286)

    Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene arginine/serine-rich protein PNISR-like Neighboring gene transketolase-like 2 Neighboring gene membrane associated ring-CH-type finger 1 Neighboring gene 60S ribosomal protein L22-like 1 pseudogene Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables preribosome binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in ribosomal large subunit biogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    translation machinery-associated protein 16

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001169102.1NP_001162573.1  translation machinery-associated protein 16

      See identical proteins and their annotated locations for NP_001162573.1

      Status: VALIDATED

      Source sequence(s)
      BI294760, CF109688, JAXUCZ010000016
      UniProtKB/TrEMBL
      A0A8I6AC99, D4AAG0
      Conserved Domains (1) summary
      pfam11176
      Location:13161
      DUF2962; Protein of unknown function (DUF2962)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086034.1 Reference GRCr8

      Range
      28003002..28021875
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017600038.3XP_017455527.1  translation machinery-associated protein 16 isoform X1

      UniProtKB/TrEMBL
      A0A8I6AC99
      Related
      ENSRNOP00000101321.1, ENSRNOT00000142434.1