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    Trim50 tripartite motif containing 50 [ Grammomys surdaster ]

    Gene ID: 114620176, updated on 15-Mar-2024

    Summary

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    Gene symbol
    Trim50
    Gene description
    tripartite motif containing 50
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Grammomys surdaster
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Grammomys
    Orthologs
    human mouse all
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    Genomic context

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    See Trim50 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    100 current NIH_TR_1.0 (GCF_004785775.1) Unplaced Scaffold NW_021604614.1 (1708930..1724365, complement)

    NW_021604614.1Genomic Context describing neighboring genes Neighboring gene huntingtin interacting protein 1 Neighboring gene nuclear envelope pore membrane protein POM 121 Neighboring gene NOP2/Sun RNA methyltransferase 5 Neighboring gene FKBP prolyl isomerase family member 6 (inactive) Neighboring gene fibroblast growth factor receptor substrate 2 pseudogene

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_021604614 Unplaced Scaffold Reference NIH_TR_1.0

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase TRIM50

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Grammomys surdaster Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NIH_TR_1.0

    Genomic

    1. NW_021604614.1 Reference NIH_TR_1.0

      Range
      1708930..1724365 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028766242.1 → XP_028622075.1  E3 ubiquitin-protein ligase TRIM50 isoform X2

      Conserved Domains (4) summary
      TIGR00618
      Location:50 → 295
      sbcc; exonuclease SbcC
      cd00021
      Location:90 → 125
      BBOX; B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction.
      cd13743
      Location:282 → 470
      SPRY_PRY_TRIM50; PRY/SPRY domain in tripartite motif-binding protein 50 (TRIM50)
      cd16605
      Location:14 → 58
      RING-HC_TRIM50_like_C-IV; RING finger, HC subclass, found in tripartite motif-containing protein TRIM50, TRIM73, TRIM74 and similar proteins

    2. XM_028766241.1 → XP_028622074.1  E3 ubiquitin-protein ligase TRIM50 isoform X1

      Conserved Domains (4) summary
      smart00502
      Location:134 → 259
      BBC; B-Box C-terminal domain
      cd00021
      Location:90 → 125
      BBOX; B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction.
      cd13743
      Location:283 → 471
      SPRY_PRY_TRIM50; PRY/SPRY domain in tripartite motif-binding protein 50 (TRIM50)
      cd16605
      Location:14 → 58
      RING-HC_TRIM50_like_C-IV; RING finger, HC subclass, found in tripartite motif-containing protein TRIM50, TRIM73, TRIM74 and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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