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    Ca12 carbonic anhydrase 12 [ Rattus rattus (black rat) ]

    Gene ID: 116908315, updated on 18-Mar-2024

    Summary

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    Gene symbol
    Ca12
    Gene description
    carbonic anhydrase 12
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus rattus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Orthologs
    human mouse all
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    Genomic context

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    See Ca12 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    100 current Rrattus_CSIRO_v1 (GCF_011064425.1) 8 NC_046161.1 (61073724..61128356)

    Chromosome 8 - NC_046161.1Genomic Context describing neighboring genes Neighboring gene F-box and leucine rich repeat protein 22 Neighboring gene ubiquitin specific peptidase 3 Neighboring gene 60S ribosomal protein L15-like Neighboring gene gamma-secretase subunit APH-1B Neighboring gene low molecular weight phosphotyrosine protein phosphatase Neighboring gene gamma-secretase subunit APH-1B-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_046161.1 Chromosome 8 Reference Rrattus_CSIRO_v1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables carbonate dehydratase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    carbonic anhydrase 12

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Rattus rattus Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rrattus_CSIRO_v1 Primary Assembly

    Genomic

    1. NC_046161.1 Reference Rrattus_CSIRO_v1 Primary Assembly

      Range
      61073724..61128356
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_032911603.1 → XP_032767494.1  carbonic anhydrase 12 isoform X1

      Conserved Domains (1) summary
      cl00012
      Location:39 → 290
      alpha_CA; Carbonic anhydrase alpha (vertebrate-like) group. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon ...

    2. XM_032911604.1 → XP_032767495.1  carbonic anhydrase 12 isoform X2

      Conserved Domains (1) summary
      cl00012
      Location:39 → 290
      alpha_CA; Carbonic anhydrase alpha (vertebrate-like) group. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon ...
    Nucleotide Protein
    Heading Accession and Version

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