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    PCSK9 proprotein convertase subtilisin/kexin type 9 [ Chelonia mydas (Green sea turtle) ]

    Gene ID: 102929839, updated on 10-Mar-2024

    Summary

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    Gene symbol
    PCSK9
    Gene description
    proprotein convertase subtilisin/kexin type 9
    Locus tag
    UY3_09314
    See related
    EnsemblRapid:ENSCMYG00015013930
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Chelonia mydas
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira; Americhelydia; Chelonioidea; Cheloniidae; Chelonia
    Orthologs
    human mouse all
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    Genomic context

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    See PCSK9 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    103 current rCheMyd1.pri.v2 (GCF_015237465.2) 8 NC_057854.1 (93213759..93231540, complement)
    102 previous assembly rCheMyd1.pri (GCF_015237465.1) 8 NC_051248.1 (93213759..93231283, complement)

    Chromosome 8 - NC_057854.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA Z39 Neighboring gene uncharacterized LOC114020047 Neighboring gene ubiquitin specific peptidase 24 Neighboring gene uncharacterized LOC122466810 Neighboring gene barttin CLCNK type accessory subunit beta

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    proprotein convertase subtilisin/kexin type 9

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Chelonia mydas Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference rCheMyd1.pri.v2 Primary Assembly

    Genomic

    1. NC_057854.1 Reference rCheMyd1.pri.v2 Primary Assembly

      Range
      93213759..93231540 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_007062195.4 → XP_007062257.3  proprotein convertase subtilisin/kexin type 9

      UniProtKB/TrEMBL
      M7BNK4
      Related
      ENSCMYP00015021534.1, ENSCMYT00015026123.1
      Conserved Domains (3) summary
      cd04077
      Location:255 → 520
      Peptidases_S8_PCSK9_ProteinaseK_like; Peptidase S8 family domain in ProteinaseK-like proteins
      cd16839
      Location:550 → 775
      PCSK9_C-CRD; proprotein convertase subtilisin/kexin type 9, C-terminal cysteine-rich domain (CRD)
      pfam05922
      Location:176 → 248
      Inhibitor_I9; Peptidase inhibitor I9
    Nucleotide Protein
    Heading Accession and Version

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