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    Opalin oligodendrocytic myelin paranodal and inner loop protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361757, updated on 9-Dec-2024

    Summary

    Official Symbol
    Opalinprovided by RGD
    Official Full Name
    oligodendrocytic myelin paranodal and inner loop proteinprovided by RGD
    Primary source
    RGD:1307776
    See related
    EnsemblRapid:ENSRNOG00000022386 AllianceGenome:RGD:1307776
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Tmem10
    Summary
    Predicted to be involved in regulation of oligodendrocyte differentiation. Predicted to be located in Golgi apparatus. Predicted to be active in cell-cell contact zone and plasma membrane. Orthologous to human OPALIN (oligodendrocytic myelin paranodal and inner loop protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 204.0) See more
    Orthologs
    NEW
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    Genomic context

    See Opalin in Genome Data Viewer
    Location:
    1q54
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (249840539..249858423, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (239891137..239909388, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (260324028..260341677, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene B-cell linker Neighboring gene uncharacterized LOC120100035 Neighboring gene DNA nucleotidylexotransferase Neighboring gene uncharacterized LOC120100036 Neighboring gene tolloid-like 2 Neighboring gene transmembrane 9 superfamily member 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in regulation of oligodendrocyte differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cell-cell contact zone IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cell-cell contact zone ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    opalin
    Names
    transmembrane protein 10

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001017386.2NP_001017386.1  opalin

      See identical proteins and their annotated locations for NP_001017386.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      Q56A26
      Related
      ENSRNOP00000029913.4, ENSRNOT00000030656.7

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      249840539..249858423 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039084537.2XP_038940465.1  opalin isoform X1