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    Vom2r5 vomeronasal 2 receptor, 5 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 679691, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Vom2r5provided by RGD
    Official Full Name
    vomeronasal 2 receptor, 5provided by RGD
    Primary source
    RGD:1585898
    See related
    EnsemblRapid:ENSRNOG00000083545 AllianceGenome:RGD:1585898
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 3.0), Testes (RPKM 1.6) and 3 other tissues See more
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    Genomic context

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    See Vom2r5 in Genome Data Viewer
    Location:
    1p13
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (2973745..2982398)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (1161906..1170559)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (804862..813613, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene vomeronasal 2 receptor, 4 Neighboring gene vomeronasal 2 receptor, pseudogene 8 Neighboring gene vomeronasal 2 receptor, 6 Neighboring gene ATPase 13A3, pseudogene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. V2R gene families degenerated in primates, dog and cow, but expanded in opossum. Young JM, et al. Trends Genet, 2007 May. PMID 17382427
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    vomeronasal 2 receptor, 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001099462.1 → NP_001092932.1  vomeronasal 2 receptor, 5 precursor

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I6AFS9
      Related
      ENSRNOP00000101894.1, ENSRNOT00000131036.1
      Conserved Domains (4) summary
      cd06365
      Location:40 → 500
      PBP1_Pheromone_receptor; Ligand-binding domain of the V2R phermone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
      pfam00003
      Location:596 → 830
      7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
      pfam01094
      Location:79 → 468
      ANF_receptor; Receptor family ligand binding region
      pfam07562
      Location:510 → 561
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      2973745..2982398
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017589699.2 → XP_017445188.1  vomeronasal 2 receptor, 5 isoform X4

      UniProtKB/TrEMBL
      A0A8I6AFS9

    2. XM_017589697.2 → XP_017445186.1  vomeronasal 2 receptor, 5 isoform X3

      UniProtKB/TrEMBL
      A0A8I6AFS9, D3ZH81

    3. XM_017589698.2 → XP_017445187.1  vomeronasal 2 receptor, 5 isoform X2

      UniProtKB/TrEMBL
      A0A8I6AFS9

    4. XM_039090209.1 → XP_038946137.1  vomeronasal 2 receptor, 5 isoform X5

      UniProtKB/TrEMBL
      A0A8I6AFS9
      Conserved Domains (2) summary
      cd15283
      Location:506 → 757
      7tmC_V2R_pheromone; vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors
      cl10011
      Location:45 → 490
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

    5. XM_063273254.1 → XP_063129324.1  vomeronasal 2 receptor, 5 isoform X1

      UniProtKB/TrEMBL
      A0A8I6AFS9

    6. XM_039090210.1 → XP_038946138.1  vomeronasal 2 receptor, 5 isoform X6

      UniProtKB/TrEMBL
      A0A8I6AP26
      Conserved Domains (1) summary
      cl10011
      Location:45 → 431
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

    7. XM_039090211.1 → XP_038946139.1  vomeronasal 2 receptor, 5 isoform X7

      UniProtKB/TrEMBL
      A0A8I6AP26
      Conserved Domains (1) summary
      cl10011
      Location:45 → 432
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

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