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    Lsm14b LSM family member 14B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100362102, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Lsm14bprovided by RGD
    Official Full Name
    LSM family member 14Bprovided by RGD
    Primary source
    RGD:1563798
    See related
    EnsemblRapid:ENSRNOG00000054557 AllianceGenome:RGD:1563798
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1563798
    Summary
    Predicted to enable RNA binding activity. Orthologous to human LSM14B (LSM family member 14B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 215.7), Heart (RPKM 213.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Lsm14b in Genome Data Viewer
    Location:
    3q43
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (187503251..187514041)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (167125633..167136417)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (175408433..175419180)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134486514 Neighboring gene U2 spliceosomal RNA Neighboring gene proteasome 20S subunit alpha 7 Neighboring gene SS18L1 subunit of BAF chromatin remodeling complex

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in maternal mRNA clearance ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in meiotic cell cycle process involved in oocyte maturation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in membraneless organelle assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in oogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in ovarian follicle development ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasmic ribonucleoprotein granule IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasmic ribonucleoprotein granule ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein LSM14 homolog B
    Names
    LSM14 homolog B
    LSM14B, SCD6 homolog B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001431812.1 → NP_001418741.1  protein LSM14 homolog B isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      A0A0G2JZY0, A6KMC9

    2. NM_001431813.1 → NP_001418742.1  protein LSM14 homolog B isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      A0A8I5ZN03, A6KMC8

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      187503251..187514041
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002729258.7 → XP_002729304.4  protein LSM14 homolog B isoform X3

      Related
      ENSRNOP00000079430.2, ENSRNOT00000119096.2
      Conserved Domains (2) summary
      cd01736
      Location:83 → 156
      LSm14_N; Like-Sm protein 14, N-terminal domain
      pfam09532
      Location:325 → 426
      FDF; FDF domain

    2. XM_063285136.1 → XP_063141206.1  protein LSM14 homolog B isoform X4

      UniProtKB/TrEMBL
      A0A8I5ZN03

    3. XM_006235828.5 → XP_006235890.2  protein LSM14 homolog B isoform X2

      UniProtKB/TrEMBL
      A0A0G2JZY0, A0A8I5Y947
      Related
      ENSRNOP00000076798.2, ENSRNOT00000108127.2
      Conserved Domains (2) summary
      cd01736
      Location:83 → 156
      LSm14_N; Like-Sm protein 14, N-terminal domain
      pfam09532
      Location:338 → 439
      FDF; FDF domain

    4. XM_006235827.5 → XP_006235889.2  protein LSM14 homolog B isoform X1

      Related
      ENSRNOP00000071227.3, ENSRNOT00000081344.3
      Conserved Domains (2) summary
      cd01736
      Location:83 → 156
      LSm14_N; Like-Sm protein 14, N-terminal domain
      pfam09532
      Location:364 → 465
      FDF; FDF domain

    5. XM_039106756.2 → XP_038962684.1  protein LSM14 homolog B isoform X5

      UniProtKB/TrEMBL
      A0A8I6A557
      Related
      ENSRNOP00000086105.2, ENSRNOT00000117745.2
      Conserved Domains (2) summary
      pfam09532
      Location:225 → 326
      FDF; FDF domain
      cl00259
      Location:83 → 119
      Sm_like; Sm and related proteins

    6. XM_039106757.2 → XP_038962685.1  protein LSM14 homolog B isoform X6

      UniProtKB/TrEMBL
      A6KMD0
      Conserved Domains (1) summary
      pfam09532
      Location:117 → 218
      FDF; FDF domain
    Nucleotide Protein Strain
    Heading Accession and Version

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