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    Pcyox1l prenylcysteine oxidase 1 like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 307396, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Pcyox1lprovided by RGD
    Official Full Name
    prenylcysteine oxidase 1 likeprovided by RGD
    Primary source
    RGD:1563290
    See related
    EnsemblRapid:ENSRNOG00000019643 AllianceGenome:RGD:1563290
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1563290
    Summary
    Predicted to enable prenylcysteine oxidase activity. Predicted to be involved in prenylated protein catabolic process. Orthologous to human PCYOX1L (prenylcysteine oxidase 1 like). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 46.6), Kidney (RPKM 32.2) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Pcyox1l in Genome Data Viewer
    Location:
    18q12.1
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (57420971..57431632, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (55150637..55161334, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (57021081..57031552, complement)

    Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene cardiac mesoderm enhancer-associated non-coding RNA Neighboring gene microRNA 143 Neighboring gene interleukin 17B Neighboring gene uncharacterized LOC134482948 Neighboring gene GrpE-like 2, mitochondrial Neighboring gene actin filament associated protein 1-like 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Defining the membrane proteome of NK cells. Ghosh D, et al. J Mass Spectrom, 2010 Jan. PMID 19946888
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables prenylcysteine oxidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in prenylated protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in prenylcysteine catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    prenylcysteine oxidase-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001134542.1 → NP_001128014.1  prenylcysteine oxidase-like precursor

      See identical proteins and their annotated locations for NP_001128014.1

      Status: PROVISIONAL

      Source sequence(s)
      BC168676
      UniProtKB/TrEMBL
      A0A8I6A461, B5DEI0
      Related
      ENSRNOP00000026584.5, ENSRNOT00000026583.7
      Conserved Domains (2) summary
      pfam07156
      Location:122 → 483
      Prenylcys_lyase; Prenylcysteine lyase
      pfam13450
      Location:31 → 96
      NAD_binding_8; NAD(P)-binding Rossmann-like domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086036.1 Reference GRCr8

      Range
      57420971..57431632 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006254806.5 → XP_006254868.1  prenylcysteine oxidase-like isoform X1

      UniProtKB/TrEMBL
      A0A8I6A461
      Conserved Domains (1) summary
      pfam07156
      Location:32 → 393
      Prenylcys_lyase; Prenylcysteine lyase

    2. XM_039096826.2 → XP_038952754.1  prenylcysteine oxidase-like isoform X2

      Conserved Domains (1) summary
      pfam07156
      Location:1 → 338
      Prenylcys_lyase; Prenylcysteine lyase

    3. XM_039096825.2 → XP_038952753.1  prenylcysteine oxidase-like isoform X2

      Conserved Domains (1) summary
      pfam07156
      Location:1 → 338
      Prenylcys_lyase; Prenylcysteine lyase
    Nucleotide Protein Strain
    Heading Accession and Version

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